
Dianavs Vayne
Diana vs Vayne is a decisive matchup in LoL patch 26.7. Diana wins with a 57.1% win rate (+14.3%) over Vayne based on 7 games. Diana holds the advantage in both the early and late game. Below you'll find the best Diana build, runes, laning stats, and strategies for the Diana vs Vayne matchup.
Diana Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Diana performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Diana vs Vayne Matchup?

Diana vs Vayne Matchup Summary
The Diana vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Diana wins with a 57.1% win rate compared to Vayne's 42.9%, giving Diana a 14.3 percentage point advantage. Diana dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Diana leads by 889 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Diana players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Diana vs Vayne Laning Phase Breakdown
Diana is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Diana holds advantages in damage, gold income and sustain, making them the stronger laner in this matchup.
Best Diana Build Against Vayne
Mercury's Treads is the optimal boots choice against Vayne, providing the mobility and stats Diana needs most in this matchup. The top-performing core items for Diana against Vayne are Luden's Echo, Randuin's Omen and Void Staff. This combination gives Diana an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Diana vs Vayne matchup.
Early Game vs Late Game
The early game (first 15 minutes) is a toss-up between Diana and Vayne, with Diana holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.
Diana is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Vayne. Extended games heavily favor Diana, whose kit and scaling make them a dominant force in team fights and objective control.
Diana holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Diana Runes Against Vayne
Running Domination primary with Sorcery secondary allows Diana to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.
Diana matchup data for League of Legends patch 26.7. The table below shows Diana's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Diana build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 51.89% | 106 | 6.0 | 896 | 12,542 | 57.5% | 47.5% | |
| 46.88% | 96 | 1.4 | 701 | 12,768 | 50.9% | 41.5% | |
| 44.21% | 95 | 1.3 | 685 | 12,661 | 54.4% | 34.7% | |
| 53.41% | 88 | 1.6 | 740 | 13,054 | 57.1% | 50.0% | |
| 40.48% | 84 | 5.8 | 860 | 12,466 | 47.1% | 36.0% | |
| 46.91% | 81 | 1.4 | 753 | 12,443 | 46.5% | 47.4% | |
| 51.90% | 79 | 6.1 | 817 | 13,192 | 63.3% | 44.9% | |
| 52.56% | 78 | 1.4 | 797 | 14,276 | 65.6% | 43.5% | |
| 48.00% | 75 | 4.3 | 850 | 11,976 | 51.2% | 43.8% | |
| 49.33% | 75 | 5.6 | 933 | 12,652 | 48.6% | 50.0% | |
| 37.84% | 74 | 1.5 | 753 | 13,378 | 43.8% | 33.3% | |
| 49.30% | 71 | 4.0 | 897 | 13,290 | 55.6% | 45.5% | |
| 56.52% | 69 | 1.7 | 779 | 13,481 | 54.8% | 57.9% | |
| 54.41% | 68 | 6.2 | 954 | 13,293 | 53.6% | 55.0% | |
| 49.23% | 65 | 5.9 | 881 | 12,352 | 54.8% | 44.1% | |
| 45.31% | 64 | 5.9 | 856 | 11,960 | 39.4% | 51.6% | |
| 46.03% | 63 | 6.2 | 865 | 12,223 | 42.9% | 48.6% | |
| 57.14% | 63 | 5.2 | 863 | 12,404 | 56.0% | 57.9% | |
| 56.14% | 57 | 6.0 | 998 | 12,198 | 48.3% | 64.3% | |
| 52.63% | 57 | 5.7 | 869 | 11,312 | 51.7% | 53.6% | |
| 51.79% | 56 | 5.8 | 897 | 12,437 | 61.3% | 40.0% | |
| 59.26% | 54 | 3.4 | 925 | 14,291 | 69.6% | 51.6% | |
| 37.74% | 53 | 1.4 | 850 | 12,885 | 38.5% | 37.0% | |
| 49.02% | 51 | 5.9 | 906 | 12,443 | 40.9% | 55.2% | |
| 43.48% | 46 | 6.0 | 795 | 11,944 | 47.6% | 40.0% | |
| 54.35% | 46 | 1.4 | 783 | 13,556 | 43.8% | 60.0% | |
| 50.00% | 44 | 6.0 | 883 | 11,931 | 63.6% | 36.4% | |
| 35.71% | 42 | 6.3 | 854 | 11,483 | 34.8% | 36.8% | |
| 53.66% | 41 | 1.6 | 801 | 12,955 | 45.8% | 64.7% | |
| 47.50% | 40 | 1.4 | 701 | 13,419 | 60.0% | 40.0% | |
| 41.03% | 39 | 3.9 | 823 | 12,599 | 41.2% | 40.9% | |
| 36.84% | 38 | 6.0 | 790 | 11,313 | 43.8% | 31.8% | |
| 59.46% | 37 | 1.2 | 742 | 13,677 | 70.6% | 50.0% | |
| 45.95% | 37 | 1.2 | 702 | 11,961 | 42.1% | 50.0% | |
| 57.14% | 35 | 6.0 | 933 | 13,408 | 84.6% | 40.9% | |
| 57.14% | 35 | 1.5 | 691 | 12,158 | 55.6% | 58.8% | |
| 52.94% | 34 | 1.1 | 704 | 12,144 | 60.0% | 47.4% | |
| 66.67% | 33 | 6.1 | 850 | 11,578 | 64.7% | 68.8% | |
| 78.79% | 33 | 5.6 | 1,001 | 12,837 | 76.9% | 80.0% | |
| 43.75% | 32 | 2.1 | 785 | 13,773 | 63.6% | 33.3% | |
| 46.88% | 32 | 1.3 | 735 | 12,193 | 50.0% | 41.7% | |
| 48.39% | 31 | 2.4 | 772 | 12,712 | 58.3% | 42.1% | |
| 41.94% | 31 | 1.6 | 871 | 12,547 | 41.2% | 42.9% | |
| 43.33% | 30 | 2.6 | 853 | 11,672 | 44.4% | 41.7% | |
| 63.33% | 30 | 5.4 | 869 | 12,216 | 50.0% | 72.2% | |
| 51.72% | 29 | 1.4 | 804 | 13,537 | 53.9% | 50.0% | |
| 48.28% | 29 | 1.6 | 909 | 12,536 | 43.8% | 53.9% | |
| 68.97% | 29 | 6.0 | 916 | 12,064 | 78.6% | 60.0% | |
| 57.14% | 28 | 1.4 | 852 | 14,019 | 60.0% | 55.6% | |
| 53.57% | 28 | 5.7 | 928 | 12,389 | 61.5% | 46.7% | |
| 48.15% | 27 | 1.4 | 778 | 14,610 | 54.5% | 43.8% | |
| 70.37% | 27 | 6.2 | 895 | 11,947 | 70.6% | 70.0% | |
| 48.15% | 27 | 1.3 | 720 | 12,155 | 58.3% | 40.0% | |
| 66.67% | 27 | 1.3 | 810 | 13,650 | 66.7% | 66.7% | |
| 34.62% | 26 | 1.8 | 778 | 13,339 | 46.1% | 23.1% | |
| 46.15% | 26 | 5.1 | 968 | 12,221 | 46.1% | 46.1% | |
| 44.00% | 25 | 1.3 | 768 | 13,357 | 50.0% | 38.5% | |
| 58.33% | 24 | 1.4 | 776 | 12,851 | 50.0% | 64.3% | |
| 54.17% | 24 | 6.0 | 967 | 14,328 | 50.0% | 56.3% | |
| 47.83% | 23 | 4.0 | 847 | 12,729 | 41.7% | 54.5% | |
| 45.45% | 22 | 5.9 | 974 | 13,214 | 62.5% | 35.7% | |
| 40.91% | 22 | 6.2 | 860 | 11,642 | 46.1% | 33.3% | |
| 61.90% | 21 | 2.1 | 726 | 11,963 | 75.0% | 44.4% | |
| 60.00% | 20 | 1.4 | 753 | 11,432 | 75.0% | 50.0% | |
| 50.00% | 20 | 2.3 | 771 | 13,596 | 50.0% | 50.0% | |
| 57.89% | 19 | 1.3 | 977 | 14,945 | 66.7% | 53.9% | |
| 42.11% | 19 | 1.3 | 682 | 12,096 | 44.4% | 40.0% | |
| 50.00% | 18 | 2.0 | 769 | 12,259 | 45.5% | 57.1% | |
| 44.44% | 18 | 1.7 | 868 | 13,915 | 71.4% | 27.3% | |
| 55.56% | 18 | 2.3 | 670 | 12,449 | 61.5% | 40.0% | |
| 52.94% | 17 | 4.7 | 829 | 13,106 | 42.9% | 60.0% | |
| 52.94% | 17 | 1.4 | 803 | 13,458 | 66.7% | 37.5% | |
| 23.53% | 17 | 1.1 | 648 | 12,158 | 33.3% | 12.5% | |
| 52.94% | 17 | 5.8 | 838 | 12,180 | 42.9% | 60.0% | |
| 50.00% | 16 | 5.8 | 1,015 | 13,104 | 50.0% | 50.0% | |
| 62.50% | 16 | 6.3 | 969 | 12,462 | 100.0% | 40.0% | |
| 66.67% | 15 | 6.2 | 927 | 14,084 | 50.0% | 69.2% | |
| 46.67% | 15 | 2.3 | 687 | 11,718 | 66.7% | 16.7% | |
| 26.67% | 15 | 4.3 | 717 | 11,868 | 28.6% | 25.0% | |
| 50.00% | 14 | 6.4 | 973 | 12,832 | 62.5% | 33.3% | |
| 42.86% | 14 | 4.7 | 837 | 12,242 | 44.4% | 40.0% | |
| 42.86% | 14 | 3.0 | 755 | 12,081 | 33.3% | 50.0% | |
| 42.86% | 14 | 1.1 | 778 | 10,999 | 40.0% | 50.0% | |
| 64.29% | 14 | 5.8 | 1,051 | 13,622 | 75.0% | 60.0% | |
| 35.71% | 14 | 3.1 | 795 | 12,923 | 40.0% | 33.3% | |
| 64.29% | 14 | 4.9 | 927 | 12,455 | 50.0% | 75.0% | |
| 69.23% | 13 | 5.0 | 939 | 12,965 | 100.0% | 60.0% | |
| 53.85% | 13 | 1.6 | 915 | 14,043 | 40.0% | 62.5% | |
| 76.92% | 13 | 6.2 | 922 | 9,860 | 80.0% | 66.7% | |
| 75.00% | 12 | 1.9 | 714 | 12,010 | 87.5% | 50.0% | |
| 66.67% | 12 | 1.8 | 720 | 12,105 | 57.1% | 80.0% | |
| 45.45% | 11 | 5.5 | 790 | 12,306 | 50.0% | 40.0% | |
| 36.36% | 11 | 4.8 | 1,035 | 13,430 | 66.7% | 25.0% | |
| 27.27% | 11 | 5.6 | 732 | 10,892 | 50.0% | 0.0% | |
| 63.64% | 11 | 5.6 | 1,149 | 12,888 | 40.0% | 83.3% | |
| 50.00% | 10 | 4.1 | 755 | 15,055 | 50.0% | 50.0% | |
| 44.44% | 9 | 1.6 | 813 | 13,797 | 33.3% | 50.0% | |
| 44.44% | 9 | 6.9 | 935 | 12,819 | 33.3% | 66.7% | |
| 66.67% | 9 | 1.1 | 746 | 11,691 | 50.0% | 100.0% | |
| 44.44% | 9 | 4.6 | 859 | 13,106 | 50.0% | 42.9% | |
| 44.44% | 9 | 6.2 | 887 | 10,783 | 66.7% | 0.0% | |
| 25.00% | 8 | 1.5 | 538 | 10,593 | 20.0% | 33.3% | |
| 28.57% | 7 | 3.1 | 738 | 10,939 | 50.0% | 0.0% | |
| 28.57% | 7 | 4.5 | 855 | 12,066 | 50.0% | 0.0% | |
| 42.86% | 7 | 2.4 | 960 | 15,101 | 50.0% | 40.0% | |
| 28.57% | 7 | 5.2 | 1,077 | 13,666 | 66.7% | 0.0% | |
| 57.14% | 7 | 4.1 | 933 | 15,594 | 50.0% | 60.0% | |
| 42.86% | 7 | 5.5 | 1,010 | 17,043 | 0.0% | 42.9% | |
| 50.00% | 6 | 5.5 | 928 | 14,680 | 0.0% | 50.0% | |
| 40.00% | 5 | 4.9 | 1,043 | 13,769 | 0.0% | 50.0% | |
| 60.00% | 5 | 0.9 | 723 | 12,175 | 50.0% | 100.0% | |
| 20.00% | 5 | 7.0 | 982 | 12,747 | 33.3% | 0.0% | |
| 40.00% | 5 | 1.2 | 735 | 13,087 | 66.7% | 0.0% | |
| 80.00% | 5 | 6.0 | 775 | 10,838 | 100.0% | 50.0% | |
| 40.00% | 5 | 3.2 | 887 | 14,902 | 33.3% | 50.0% | |
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Diana vs Vayne - Frequently Asked Questions
How does Diana do against Vayne in League of Legends?
Diana wins the Diana vs Vayne matchup with a 57.1% win rate compared to Vayne's 42.9%, a 14.3 percentage point difference. This data is based on 7 recent ranked games in patch 26.7.
How does Diana do against Vayne in the early game?
In the early game, Diana has the advantage against Vayne with a 50.0% win rate versus 50.0%. Diana players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Diana do against Vayne in the late game?
In the late game, Diana takes over the Diana vs Vayne matchup with a 60.0% win rate compared to 40.0%. Diana scales better into team fights and objective contests after 25 minutes.
Who wins the Diana vs Vayne matchup?
Diana wins the matchup against Vayne with a 57.1% win rate in League of Legends patch 26.7. The 14.3 percentage point advantage means Diana is significantly favored in this lane matchup based on 7 games analyzed.
What is the best Diana build against Vayne?
The best Diana build against Vayne includes Luden's Echo, Randuin's Omen, Void Staff with Mercury's Treads. Check the matchup breakdown above for the full item path and build order.
What are the best Diana runes against Vayne?
The best Diana runes against Vayne use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Diana vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Diana counter Vayne?
Yes, Diana has a favorable matchup against Vayne with a 57.1% win rate. Diana strongly counters Vayne in lane based on current patch 26.7 data.
How do I play Diana against Vayne?
When playing Diana against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.
