Vayne - League of Legends Champion
Win Rate
50.4%
Pick Rate
4.9%

Vaynevs Diana

BMarksmanAssassin
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 5, 2026
MethodologyData Methodology

Vayne vs Diana is a decisive matchup in LoL patch 26.11. Diana wins with a 60.0% win rate (+20.0%) over Vayne based on 10 games. Vayne wins the early laning phase while Diana scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Diana matchup.

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Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 40.0% win rate in this matchup
Vayne
40.0% WR
VS
Diana vs Vayne matchup - 60.0% win rate
Diana
60.0% WR

Who Wins the Vayne vs Diana Matchup?

Diana wins the Vayne vs Diana matchup
Winner
Diana
Matches: 10
40.0%
Win Rate
60.0%
4.6
CS / min
4.1
708
DMG / min
839
11,732
Gold / game
12,700
236
Heal / min
154
406
DMG Mitigated / min
884
0.5
CC / min
0.4
50.0%
Early Game WR
50.0%
25.0%
Late Game WR
75.0%

Vayne vs Diana Matchup Summary

The Vayne vs Diana matchup is a decisive matchup in League of Legends ranked play. Based on 10 recent matches analyzed, Diana wins with a 60.0% win rate compared to Vayne's 40.0%, giving Diana a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Diana outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Diana reaches their power spikes, while Diana should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Diana leads by 395 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Diana has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Diana overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Diana Laning Phase Breakdown

Diana wins the laning phase against Vayne in League of Legends

Diana is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Diana holds advantages in damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
4.6Vayne
4.1Diana
Vayne edges out Diana by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 7 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Vayne.
Damage
708Vayne
839Diana
Diana heavily out-damages Vayne by 130 DMG/min, dominating both short trades and all-in fights. Vayne should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Diana's sustained damage advantage take over.
Economy
11,732Vayne
12,700Diana
Diana generates a commanding 967 more gold per game than Vayne. This substantial economic advantage means Diana consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Vayne should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.5Vayne
0.4Diana
Both Vayne and Diana provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
642Vayne
1,038Diana
Diana vastly out-sustains Vayne, healing and mitigating 395 more damage per minute. This massive durability gap means Diana can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Diana

Berserker's Greaves is the optimal boots choice against Diana, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Diana are Kraken Slayer, Blade of The Ruined King and Guinsoo's Rageblade. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Diana. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Diana matchup.

Early Game vs Late Game

Early Game
Vayne
50.0%
+0.0% advantage
Vayne early game win rateVayne50.0%
Diana early game win rateDiana50.0%
Late Game
Diana
75.0%
+50.0% advantage
Vayne late game win rateVayne25.0%
Diana late game win rateDiana75.0%

The early game (first 15 minutes) is a toss-up between Vayne and Diana, with Vayne holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Diana is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Vayne. Extended games heavily favor Diana, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Vayne has the edge early, but Diana gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Vayne Runes Against Diana

Precision rune tree - Vayne primary runes vs DianaPrecision
Press the Attack - best Vayne rune vs DianaTriumph - best Vayne rune vs DianaLegend: Alacrity - best Vayne rune vs DianaCoup de Grace - best Vayne rune vs Diana
Inspiration rune tree - Vayne secondary runes vs DianaInspiration
Magical Footwear - best Vayne rune vs DianaCosmic Insight - best Vayne rune vs Diana
100.0% WR

The Precision and Inspiration rune setup gives Vayne the best tools to compete against Diana in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Vayne matchup data for League of Legends patch 26.11. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.01%4766.078912,87544.3%47.4%
47.20%4476.079112,72545.4%48.6%
46.26%4285.779612,71544.9%47.3%
53.92%3956.085712,96853.2%54.6%
47.85%3726.289413,18946.8%48.6%
52.99%3516.284313,14252.5%53.4%
52.98%2856.390413,45646.2%58.8%
53.90%2696.387713,73748.2%58.0%
52.38%1895.988612,46846.1%58.2%
51.92%1566.591311,98950.0%53.4%
54.30%1516.185913,22758.5%51.2%
50.33%1516.180413,00743.8%55.2%
45.95%1485.978013,60345.3%46.3%
45.38%1306.177613,08138.2%50.7%
47.83%1156.481213,76538.5%52.6%
42.61%1156.178112,08234.0%49.2%
50.88%1145.886612,98941.2%58.7%
45.19%1046.489913,17548.7%43.1%
59.80%1026.585413,18963.5%56.0%
31.00%1005.563510,36011.1%47.3%
45.83%965.885713,16444.4%46.7%
50.53%956.31,12012,73751.6%50.0%
58.06%936.379613,00854.8%60.8%
44.09%935.862511,33042.4%45.0%
45.56%905.883011,35543.6%47.1%
45.98%876.385113,57237.9%50.0%
55.81%866.189910,74843.2%65.3%
55.95%846.21,29211,54651.4%59.2%
56.41%786.388313,43557.1%55.8%
54.84%625.981412,06158.3%52.6%
45.76%596.287712,77548.0%44.1%
51.92%526.091311,59248.1%56.0%
45.10%516.592112,14440.9%48.3%
52.00%506.087513,62147.8%55.6%
35.42%486.272110,98228.0%43.5%
58.33%486.198911,81064.0%52.2%
45.83%486.21,00510,83851.9%38.1%
50.00%466.297013,36447.4%51.9%
58.70%466.291413,67162.5%54.5%
54.55%446.287414,06357.1%53.3%
44.19%436.683913,74455.0%34.8%
26.19%425.987411,67823.5%28.0%
48.78%415.983611,64443.5%55.6%
52.50%405.683813,60737.5%56.3%
38.46%396.785410,96150.0%28.6%
41.03%396.07439,57128.6%55.6%
67.57%376.589811,52662.5%76.9%
45.95%375.683211,99840.0%50.0%
52.94%346.475912,24550.0%54.5%
52.94%346.41,05111,47452.6%53.3%
66.67%336.393813,52461.5%70.0%
48.48%336.478411,26950.0%46.1%
48.48%336.597913,30562.5%44.0%
40.63%325.382011,34442.1%38.5%
62.50%325.779613,16341.7%75.0%
40.63%326.267610,36931.6%53.9%
58.06%316.484912,13864.3%52.9%
53.33%305.685512,15255.6%52.4%
60.00%306.095312,30876.9%47.1%
43.33%306.664611,44137.5%50.0%
55.56%275.379211,00650.0%60.0%
48.15%276.283411,46543.8%54.5%
50.00%265.969311,80141.7%57.1%
50.00%266.171011,42146.1%53.9%
30.77%265.370011,00127.3%33.3%
50.00%265.883412,30154.5%46.7%
48.00%256.081612,91020.0%66.7%
44.00%256.475811,84450.0%38.5%
54.17%246.399112,32564.3%40.0%
45.83%246.085011,12557.1%30.0%
56.52%235.761010,29945.5%66.7%
45.45%226.573412,18438.5%55.6%
40.91%226.080612,81544.4%38.5%
42.11%196.292010,37245.5%37.5%
63.16%196.387012,58950.0%72.7%
42.11%195.881712,14257.1%33.3%
61.11%185.61,00813,43366.7%58.3%
62.50%166.188511,54762.5%62.5%
80.00%152.288517,36850.0%84.6%
53.33%156.498513,30150.0%54.5%
60.00%156.583311,24437.5%85.7%
46.67%156.687611,53050.0%42.9%
46.67%155.491613,99225.0%54.5%
42.86%146.482413,96675.0%30.0%
42.86%146.084113,4470.0%66.7%
53.85%136.584913,506100.0%33.3%
46.15%135.275011,57950.0%42.9%
66.67%125.61,02512,92880.0%57.1%
33.33%126.092711,90033.3%33.3%
54.55%115.61,00213,29850.0%57.1%
63.64%116.164210,20450.0%80.0%
54.55%112.982014,06866.7%40.0%
81.82%116.277512,783100.0%71.4%
54.55%113.484613,74333.3%62.5%
54.55%115.576111,64971.4%25.0%
45.45%115.69159,80875.0%28.6%
40.00%104.670811,73250.0%25.0%
60.00%105.782012,59750.0%62.5%
50.00%103.877113,23733.3%57.1%
40.00%105.592611,89340.0%40.0%
66.67%93.81,03913,79866.7%66.7%
33.33%96.11,07613,2730.0%50.0%
55.56%96.793013,145100.0%20.0%
33.33%96.085513,01833.3%33.3%
55.56%93.986012,86033.3%66.7%
50.00%85.887014,56550.0%50.0%
62.50%87.368411,84766.7%50.0%
50.00%83.288313,47975.0%25.0%
25.00%85.26909,10216.7%50.0%
37.50%85.85269,89450.0%25.0%
57.14%74.076010,75033.3%75.0%
71.43%73.674311,42580.0%50.0%
42.86%74.572311,69733.3%50.0%
28.57%74.567612,0460.0%40.0%
50.00%63.578115,0220.0%60.0%
33.33%66.882313,7790.0%50.0%
33.33%62.998912,89833.3%33.3%
66.67%65.91,00614,14350.0%75.0%
20.00%54.75778,99933.3%0.0%
40.00%52.161112,29050.0%0.0%
40.00%56.41,17614,5940.0%50.0%
80.00%56.21,02413,762100.0%66.7%
40.00%55.996213,2480.0%50.0%
40.00%56.06739,21850.0%0.0%
40.00%56.47269,89240.0%0.0%

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Vayne vs Diana - Frequently Asked Questions

How does Vayne do against Diana in League of Legends?

Diana wins the Vayne vs Diana matchup with a 60.0% win rate compared to Vayne's 40.0%, a 20.0 percentage point difference. This data is based on 10 recent ranked games in patch 26.11.

How does Vayne do against Diana in the early game?

In the early game, Vayne has the advantage against Diana with a 50.0% win rate versus 50.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Diana in the late game?

In the late game, Diana takes over the Vayne vs Diana matchup with a 75.0% win rate compared to 25.0%. Diana scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Diana matchup?

Diana wins the matchup against Vayne with a 60.0% win rate in League of Legends patch 26.11. The 20.0 percentage point advantage means Diana is significantly favored in this lane matchup based on 10 games analyzed.

What is the best Vayne build against Diana?

The best Vayne build against Diana includes Kraken Slayer, Blade of The Ruined King, Guinsoo's Rageblade with Berserker's Greaves. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Diana?

The best Vayne runes against Diana use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Diana matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Diana?

No, Vayne struggles against Diana with only a 40.0% win rate. Diana has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Diana's lead.

How do I play Vayne against Diana?

When playing Vayne against Diana, play cautiously and avoid Diana's power spikes. Look for jungle assistance and team-dependent plays since Diana has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.