Vayne - League of Legends Champion
Win Rate
49.5%
Pick Rate
5.3%

Vaynevs Gwen

DMarksmanAssassin
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 25, 2026
MethodologyData Methodology

Vayne vs Gwen is a decisive matchup in LoL patch 26.7. Vayne wins with a 73.3% win rate (+46.7%) over Gwen based on 15 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Gwen matchup.

Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Gwen - 73.3% win rateGwen(73.3%)
Vayne - 73.3% win rate in this matchup
Vayne
73.3% WR
VS
Gwen vs Vayne matchup - 26.7% win rate
Gwen
26.7% WR

Who Wins the Vayne vs Gwen Matchup?

Vayne wins the Vayne vs Gwen matchup
Winner
Vayne
Matches: 15
73.3%
Win Rate
26.7%
6.4
CS / min
6.1
851
DMG / min
658
12,621
Gold / game
11,470
255
Heal / min
169
519
DMG Mitigated / min
837
0.4
CC / min
0.2
77.8%
Early Game WR
22.2%
66.7%
Late Game WR
33.3%

Vayne vs Gwen Matchup Summary

The Vayne vs Gwen matchup is a decisive matchup in League of Legends ranked play. Based on 15 recent matches analyzed, Vayne wins with a 73.3% win rate compared to Gwen's 26.7%, giving Vayne a 46.7 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Gwen players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Vayne leads by 0.2s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Gwen and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Gwen away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Gwen Laning Phase Breakdown

Vayne wins the laning phase against Gwen in League of Legends

Vayne is favored during the laning phase against Gwen, winning 4 out of 5 key stat categories. Vayne holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.4Vayne
6.1Gwen
Vayne and Gwen farm at nearly identical rates in this matchup, with only a 0.2 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
851Vayne
658Gwen
Vayne heavily out-damages Gwen by 192 DMG/min, dominating both short trades and all-in fights. Gwen should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
12,621Vayne
11,470Gwen
Vayne generates a commanding 1,151 more gold per game than Gwen. This substantial economic advantage means Vayne consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Gwen should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.4Vayne
0.2Gwen
Both Vayne and Gwen provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
775Vayne
1,006Gwen
Gwen vastly out-sustains Vayne, healing and mitigating 232 more damage per minute. This massive durability gap means Gwen can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Gwen

Boots of Swiftness is the optimal boots choice against Gwen, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Gwen are Essence Reaver, Stormrazor and Experimental Hexplate. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 3 games — well above average and making it the top item path against Gwen. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Gwen matchup.

Early Game vs Late Game

Early Game
Vayne
77.8%
+55.6% advantage
Vayne early game win rateVayne77.8%
Gwen early game win rateGwen22.2%
Late Game
Vayne
66.7%
+33.3% advantage
Vayne late game win rateVayne66.7%
Gwen late game win rateGwen33.3%

Vayne dominates the early game (first 15 minutes) with a commanding 77.8% win rate — a 55.6 percentage point lead over Gwen. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Vayne is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Gwen. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Gwen players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vayne Runes Against Gwen

Precision rune tree - Vayne primary runes vs GwenPrecision
Lethal Tempo - best Vayne rune vs GwenTriumph - best Vayne rune vs GwenLegend: Bloodline - best Vayne rune vs GwenCut Down - best Vayne rune vs Gwen
Inspiration rune tree - Vayne secondary runes vs GwenInspiration
Biscuit Delivery - best Vayne rune vs GwenJack Of All Trades - best Vayne rune vs Gwen
100.0% WR

Running Precision primary with Inspiration secondary allows Vayne to press their advantage against Gwen, amplifying the strengths that make this a favorable matchup.


Vayne matchup data for League of Legends patch 26.7. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.02%3576.081713,23145.3%52.0%
52.47%3246.289813,59649.3%55.2%
48.09%3146.283212,81944.0%52.7%
49.01%3025.982512,93747.5%50.3%
52.94%2726.083913,07152.8%53.1%
45.37%2276.496014,25446.9%44.2%
50.00%2226.493713,71750.0%50.0%
52.71%2036.585613,74148.9%56.0%
52.32%1516.582813,28755.4%49.4%
58.39%1496.695312,70051.6%63.5%
51.30%1155.881313,71761.5%42.9%
47.71%1096.088213,23938.2%57.4%
55.67%976.488012,62559.6%51.1%
51.55%976.380612,73552.5%50.0%
50.00%945.983213,59546.7%53.1%
36.36%886.279012,98330.0%41.7%
47.44%786.692813,28446.3%48.6%
61.33%756.692412,10266.7%55.6%
55.56%726.185813,24745.2%63.4%
57.35%686.085313,57456.0%58.1%
36.76%686.288112,39436.7%36.8%
52.54%596.383712,51848.5%57.7%
42.37%596.287012,82834.4%51.9%
38.60%575.760511,22540.0%37.0%
37.50%565.560110,77030.4%42.4%
43.40%536.21,04512,46744.4%42.3%
44.00%506.188613,06147.8%40.7%
53.06%496.11,21413,80450.0%55.2%
65.91%446.186913,29266.7%65.4%
56.82%445.692114,04761.1%53.9%
43.18%445.799611,54831.3%50.0%
50.00%406.384813,58435.3%60.9%
55.00%405.989314,58823.1%70.4%
57.50%406.395114,24860.0%56.7%
48.72%396.595213,49157.9%40.0%
57.89%386.01,02912,41355.0%61.1%
42.11%386.192313,74144.4%40.0%
54.05%377.092811,69252.4%56.3%
40.54%375.880412,22541.2%40.0%
40.00%355.71,14111,80838.9%41.2%
55.88%346.585611,12557.9%53.3%
50.00%326.098613,59966.7%43.5%
66.67%306.289612,54050.0%81.3%
56.67%306.298113,89653.9%58.8%
48.28%296.785812,18028.6%66.7%
55.17%296.31,02413,69462.5%46.1%
51.85%275.798412,39145.5%56.3%
61.54%266.185111,71961.5%61.5%
64.00%256.080811,77055.6%68.8%
44.00%256.892712,26342.9%45.5%
33.33%246.483511,60541.7%25.0%
56.52%235.592112,42462.5%53.3%
43.48%236.383712,92160.0%30.8%
40.91%226.678811,10141.7%40.0%
52.38%215.992313,47740.0%63.6%
60.00%205.290914,35220.0%73.3%
47.37%196.91,00811,89263.6%25.0%
50.00%186.273213,04560.0%37.5%
50.00%186.21,05312,78455.6%44.4%
44.44%186.483711,79542.9%45.5%
50.00%185.875412,37328.6%63.6%
76.47%176.91,02114,29680.0%75.0%
29.41%176.982911,89737.5%22.2%
41.18%176.086215,19160.0%33.3%
43.75%166.083811,77362.5%25.0%
56.25%166.690711,52757.1%55.6%
37.50%165.465913,20816.7%50.0%
68.75%166.793713,92583.3%60.0%
53.33%155.968611,41937.5%71.4%
73.33%156.485112,62177.8%66.7%
50.00%145.785111,11416.7%75.0%
42.86%144.364512,05114.3%71.4%
53.85%133.388514,16275.0%44.4%
53.85%135.71,05513,76250.0%55.6%
58.33%125.656210,02757.1%60.0%
25.00%124.586213,08325.0%25.0%
50.00%126.378413,32833.3%66.7%
27.27%116.277113,46233.3%25.0%
63.64%116.387415,82666.7%62.5%
36.36%116.665110,70650.0%20.0%
45.45%115.591912,62950.0%40.0%
72.73%116.474510,85071.4%75.0%
45.45%116.01,06414,50840.0%50.0%
70.00%106.699613,49075.0%66.7%
40.00%106.887613,21633.3%50.0%
55.56%96.393712,28633.3%100.0%
44.44%96.21,07715,702100.0%28.6%
33.33%96.877411,06920.0%50.0%
25.00%85.569310,37825.0%25.0%
50.00%85.99738,78533.3%100.0%
37.50%81.983414,72733.3%40.0%
42.86%75.690112,809100.0%20.0%
0.00%76.655810,7000.0%0.0%
42.86%74.665114,53850.0%40.0%
71.43%76.168213,12675.0%66.7%
57.14%75.588812,31625.0%100.0%
57.14%75.489512,10050.0%66.7%
42.86%74.077311,64333.3%50.0%
57.14%72.51,31315,57625.0%100.0%
33.33%64.65709,10525.0%50.0%
66.67%65.91,08915,49350.0%75.0%
50.00%65.776213,18250.0%50.0%
50.00%61.989114,832100.0%40.0%
16.67%65.384410,4420.0%33.3%
0.00%65.979510,7240.0%0.0%
83.33%66.196311,361100.0%50.0%
50.00%66.380413,574100.0%40.0%
40.00%54.793914,778100.0%0.0%
60.00%51.71,19517,6480.0%75.0%
20.00%51.56919,37833.3%0.0%
60.00%55.31,10015,380100.0%50.0%
20.00%56.891512,5530.0%33.3%
40.00%56.51,02117,6030.0%40.0%

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Vayne vs Gwen - Frequently Asked Questions

How does Vayne do against Gwen in League of Legends?

Vayne wins the Vayne vs Gwen matchup with a 73.3% win rate compared to Gwen's 26.7%, a 46.7 percentage point difference. This data is based on 15 recent ranked games in patch 26.7.

How does Vayne do against Gwen in the early game?

In the early game, Vayne has the advantage against Gwen with a 77.8% win rate versus 22.2%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Gwen in the late game?

In the late game, Vayne takes over the Vayne vs Gwen matchup with a 66.7% win rate compared to 33.3%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Gwen matchup?

Vayne wins the matchup against Gwen with a 73.3% win rate in League of Legends patch 26.7. The 46.7 percentage point advantage means Vayne is significantly favored in this lane matchup based on 15 games analyzed.

What is the best Vayne build against Gwen?

The best Vayne build against Gwen includes Essence Reaver, Stormrazor, Experimental Hexplate with Boots of Swiftness. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Gwen?

The best Vayne runes against Gwen use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Gwen matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Gwen?

Yes, Vayne has a favorable matchup against Gwen with a 73.3% win rate. Vayne strongly counters Gwen in lane based on current patch 26.7 data.

How do I play Vayne against Gwen?

When playing Vayne against Gwen, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.