Vayne - League of Legends Champion
Win Rate
49.1%
Pick Rate
4.7%

Vaynevs Gwen

DMarksmanAssassin
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 10, 2026
MethodologyData Methodology

Vayne vs Gwen is a decisive matchup in LoL patch 26.11. Vayne wins with a 55.6% win rate (+11.1%) over Gwen based on 27 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Gwen matchup.

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Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 55.6% win rate in this matchup
Vayne
55.6% WR
VS
Gwen vs Vayne matchup - 44.4% win rate
Gwen
44.4% WR

Who Wins the Vayne vs Gwen Matchup?

Vayne wins the Vayne vs Gwen matchup
Winner
Vayne
Matches: 27
55.6%
Win Rate
44.4%
5.3
CS / min
5.9
792
DMG / min
922
11,006
Gold / game
12,311
260
Heal / min
390
495
DMG Mitigated / min
983
0.4
CC / min
0.3
50.0%
Early Game WR
50.0%
60.0%
Late Game WR
40.0%

Vayne vs Gwen Matchup Summary

The Vayne vs Gwen matchup is a decisive matchup in League of Legends ranked play. Based on 27 recent matches analyzed, Vayne wins with a 55.6% win rate compared to Gwen's 44.4%, giving Vayne a 11.1 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Gwen players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Gwen leads by 618 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Gwen and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Gwen away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Gwen Laning Phase Breakdown

Gwen wins the laning phase against Vayne in League of Legends

Gwen is favored during the laning phase against Vayne, winning 4 out of 5 key stat categories. Gwen holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
5.3Vayne
5.9Gwen
Gwen edges out Vayne by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 8 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Gwen.
Damage
792Vayne
922Gwen
Gwen heavily out-damages Vayne by 131 DMG/min, dominating both short trades and all-in fights. Vayne should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Gwen's sustained damage advantage take over.
Economy
11,006Vayne
12,311Gwen
Gwen generates a commanding 1,305 more gold per game than Vayne. This substantial economic advantage means Gwen consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Vayne should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.4Vayne
0.3Gwen
Both Vayne and Gwen provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
755Vayne
1,373Gwen
Gwen vastly out-sustains Vayne, healing and mitigating 618 more damage per minute. This massive durability gap means Gwen can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Gwen

Plated Steelcaps is the optimal boots choice against Gwen, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Gwen are Blade of The Ruined King, Guinsoo's Rageblade and Experimental Hexplate. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Gwen. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Gwen matchup.

Early Game vs Late Game

Early Game
Vayne
50.0%
+0.0% advantage
Vayne early game win rateVayne50.0%
Gwen early game win rateGwen50.0%
Late Game
Vayne
60.0%
+20.0% advantage
Vayne late game win rateVayne60.0%
Gwen late game win rateGwen40.0%

The early game (first 15 minutes) is a toss-up between Vayne and Gwen, with Vayne holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Vayne is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Gwen. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Gwen players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vayne Runes Against Gwen

Precision rune tree - Vayne primary runes vs GwenPrecision
Fleet Footwork - best Vayne rune vs GwenAbsorb Life - best Vayne rune vs GwenLegend: Alacrity - best Vayne rune vs GwenCut Down - best Vayne rune vs Gwen
Sorcery rune tree - Vayne secondary runes vs GwenSorcery
Celerity - best Vayne rune vs GwenNimbus Cloak - best Vayne rune vs Gwen
100.0% WR

Running Precision primary with Sorcery secondary allows Vayne to press their advantage against Gwen, amplifying the strengths that make this a favorable matchup.


Vayne matchup data for League of Legends patch 26.11. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.01%4766.078912,87544.3%47.4%
47.20%4476.079112,72545.4%48.6%
46.26%4285.779612,71544.9%47.3%
53.92%3956.085712,96853.2%54.6%
47.85%3726.289413,18946.8%48.6%
52.99%3516.284313,14252.5%53.4%
52.98%2856.390413,45646.2%58.8%
53.90%2696.387713,73748.2%58.0%
52.38%1895.988612,46846.1%58.2%
51.92%1566.591311,98950.0%53.4%
54.30%1516.185913,22758.5%51.2%
50.33%1516.180413,00743.8%55.2%
45.95%1485.978013,60345.3%46.3%
45.38%1306.177613,08138.2%50.7%
47.83%1156.481213,76538.5%52.6%
42.61%1156.178112,08234.0%49.2%
50.88%1145.886612,98941.2%58.7%
45.19%1046.489913,17548.7%43.1%
59.80%1026.585413,18963.5%56.0%
31.00%1005.563510,36011.1%47.3%
45.83%965.885713,16444.4%46.7%
50.53%956.31,12012,73751.6%50.0%
58.06%936.379613,00854.8%60.8%
44.09%935.862511,33042.4%45.0%
45.56%905.883011,35543.6%47.1%
45.98%876.385113,57237.9%50.0%
55.81%866.189910,74843.2%65.3%
55.95%846.21,29211,54651.4%59.2%
56.41%786.388313,43557.1%55.8%
54.84%625.981412,06158.3%52.6%
45.76%596.287712,77548.0%44.1%
51.92%526.091311,59248.1%56.0%
45.10%516.592112,14440.9%48.3%
52.00%506.087513,62147.8%55.6%
35.42%486.272110,98228.0%43.5%
58.33%486.198911,81064.0%52.2%
45.83%486.21,00510,83851.9%38.1%
50.00%466.297013,36447.4%51.9%
58.70%466.291413,67162.5%54.5%
54.55%446.287414,06357.1%53.3%
44.19%436.683913,74455.0%34.8%
26.19%425.987411,67823.5%28.0%
48.78%415.983611,64443.5%55.6%
52.50%405.683813,60737.5%56.3%
38.46%396.785410,96150.0%28.6%
41.03%396.07439,57128.6%55.6%
67.57%376.589811,52662.5%76.9%
45.95%375.683211,99840.0%50.0%
52.94%346.475912,24550.0%54.5%
52.94%346.41,05111,47452.6%53.3%
66.67%336.393813,52461.5%70.0%
48.48%336.478411,26950.0%46.1%
48.48%336.597913,30562.5%44.0%
40.63%325.382011,34442.1%38.5%
62.50%325.779613,16341.7%75.0%
40.63%326.267610,36931.6%53.9%
58.06%316.484912,13864.3%52.9%
53.33%305.685512,15255.6%52.4%
60.00%306.095312,30876.9%47.1%
43.33%306.664611,44137.5%50.0%
55.56%275.379211,00650.0%60.0%
48.15%276.283411,46543.8%54.5%
50.00%265.969311,80141.7%57.1%
50.00%266.171011,42146.1%53.9%
30.77%265.370011,00127.3%33.3%
50.00%265.883412,30154.5%46.7%
48.00%256.081612,91020.0%66.7%
44.00%256.475811,84450.0%38.5%
54.17%246.399112,32564.3%40.0%
45.83%246.085011,12557.1%30.0%
56.52%235.761010,29945.5%66.7%
45.45%226.573412,18438.5%55.6%
40.91%226.080612,81544.4%38.5%
42.11%196.292010,37245.5%37.5%
63.16%196.387012,58950.0%72.7%
42.11%195.881712,14257.1%33.3%
61.11%185.61,00813,43366.7%58.3%
62.50%166.188511,54762.5%62.5%
80.00%152.288517,36850.0%84.6%
53.33%156.498513,30150.0%54.5%
60.00%156.583311,24437.5%85.7%
46.67%156.687611,53050.0%42.9%
46.67%155.491613,99225.0%54.5%
42.86%146.482413,96675.0%30.0%
42.86%146.084113,4470.0%66.7%
53.85%136.584913,506100.0%33.3%
46.15%135.275011,57950.0%42.9%
66.67%125.61,02512,92880.0%57.1%
33.33%126.092711,90033.3%33.3%
54.55%115.61,00213,29850.0%57.1%
63.64%116.164210,20450.0%80.0%
54.55%112.982014,06866.7%40.0%
81.82%116.277512,783100.0%71.4%
54.55%113.484613,74333.3%62.5%
54.55%115.576111,64971.4%25.0%
45.45%115.69159,80875.0%28.6%
40.00%104.670811,73250.0%25.0%
60.00%105.782012,59750.0%62.5%
50.00%103.877113,23733.3%57.1%
40.00%105.592611,89340.0%40.0%
66.67%93.81,03913,79866.7%66.7%
33.33%96.11,07613,2730.0%50.0%
55.56%96.793013,145100.0%20.0%
33.33%96.085513,01833.3%33.3%
55.56%93.986012,86033.3%66.7%
50.00%85.887014,56550.0%50.0%
62.50%87.368411,84766.7%50.0%
50.00%83.288313,47975.0%25.0%
25.00%85.26909,10216.7%50.0%
37.50%85.85269,89450.0%25.0%
57.14%74.076010,75033.3%75.0%
71.43%73.674311,42580.0%50.0%
42.86%74.572311,69733.3%50.0%
28.57%74.567612,0460.0%40.0%
50.00%63.578115,0220.0%60.0%
33.33%66.882313,7790.0%50.0%
33.33%62.998912,89833.3%33.3%
66.67%65.91,00614,14350.0%75.0%
20.00%54.75778,99933.3%0.0%
40.00%52.161112,29050.0%0.0%
40.00%56.41,17614,5940.0%50.0%
80.00%56.21,02413,762100.0%66.7%
40.00%55.996213,2480.0%50.0%
40.00%56.06739,21850.0%0.0%
40.00%56.47269,89240.0%0.0%

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Vayne vs Gwen - Frequently Asked Questions

How does Vayne do against Gwen in League of Legends?

Vayne wins the Vayne vs Gwen matchup with a 55.6% win rate compared to Gwen's 44.4%, a 11.1 percentage point difference. This data is based on 27 recent ranked games in patch 26.11.

How does Vayne do against Gwen in the early game?

In the early game, Vayne has the advantage against Gwen with a 50.0% win rate versus 50.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Gwen in the late game?

In the late game, Vayne takes over the Vayne vs Gwen matchup with a 60.0% win rate compared to 40.0%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Gwen matchup?

Vayne wins the matchup against Gwen with a 55.6% win rate in League of Legends patch 26.11. The 11.1 percentage point advantage means Vayne is significantly favored in this lane matchup based on 27 games analyzed.

What is the best Vayne build against Gwen?

The best Vayne build against Gwen includes Blade of The Ruined King, Guinsoo's Rageblade, Experimental Hexplate with Plated Steelcaps. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Gwen?

The best Vayne runes against Gwen use the Precision primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Gwen matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Gwen?

Yes, Vayne has a favorable matchup against Gwen with a 55.6% win rate. Vayne strongly counters Gwen in lane based on current patch 26.11 data.

How do I play Vayne against Gwen?

When playing Vayne against Gwen, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.