Vayne - League of Legends Champion
Win Rate
48.8%
Pick Rate
5.3%

Vaynevs Ekko

DMarksmanAssassin
Patch26.10
Matches683,599
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 18, 2026
MethodologyData Methodology

Vayne vs Ekko is a decisive matchup in LoL patch 26.10. Vayne wins with a 55.6% win rate (+11.1%) over Ekko based on 9 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Ekko matchup.

Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Ekko - 55.6% win rateEkko(55.6%)
Vayne - 55.6% win rate in this matchup
Vayne
55.6% WR
VS
Ekko vs Vayne matchup - 44.4% win rate
Ekko
44.4% WR

Who Wins the Vayne vs Ekko Matchup?

Vayne wins the Vayne vs Ekko matchup
Winner
Vayne
Matches: 9
55.6%
Win Rate
44.4%
4.9
CS / min
4.0
1,049
DMG / min
895
14,742
Gold / game
12,877
279
Heal / min
328
526
DMG Mitigated / min
916
0.5
CC / min
0.8
50.0%
Early Game WR
50.0%
57.1%
Late Game WR
42.9%

Vayne vs Ekko Matchup Summary

The Vayne vs Ekko matchup is a decisive matchup in League of Legends ranked play. Based on 9 recent matches analyzed, Vayne wins with a 55.6% win rate compared to Ekko's 44.4%, giving Vayne a 11.1 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Ekko players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Ekko leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Ekko and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Ekko away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Ekko Laning Phase Breakdown

Vayne wins the laning phase against Ekko in League of Legends

Vayne is favored during the laning phase against Ekko, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
4.9Vayne
4.0Ekko
Vayne significantly out-farms Ekko by 0.9 CS per minute, accumulating an estimated 13 CS lead by mid game. This substantial farming gap gives Vayne a major gold advantage and earlier item completions. Ekko players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
1,049Vayne
895Ekko
Vayne heavily out-damages Ekko by 154 DMG/min, dominating both short trades and all-in fights. Ekko should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
14,742Vayne
12,877Ekko
Vayne generates a commanding 1,865 more gold per game than Ekko. This substantial economic advantage means Vayne consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Ekko should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.5Vayne
0.8Ekko
Both Vayne and Ekko provide similar amounts of crowd control (0.3s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
805Vayne
1,244Ekko
Ekko vastly out-sustains Vayne, healing and mitigating 439 more damage per minute. This massive durability gap means Ekko can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Ekko

Immortal Path is the optimal boots choice against Ekko, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Ekko are Essence Reaver, Blade of The Ruined King and Experimental Hexplate. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Ekko. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Ekko matchup.

Early Game vs Late Game

Early Game
Vayne
50.0%
+0.0% advantage
Vayne early game win rateVayne50.0%
Ekko early game win rateEkko50.0%
Late Game
Vayne
57.1%
+14.3% advantage
Vayne late game win rateVayne57.1%
Ekko late game win rateEkko42.9%

The early game (first 15 minutes) is a toss-up between Vayne and Ekko, with Vayne holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Vayne is far superior in the late game (25+ minutes), boasting a 57.1% win rate — 14.3 points above Ekko. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Ekko players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vayne Runes Against Ekko

Precision rune tree - Vayne primary runes vs EkkoPrecision
Press the Attack - best Vayne rune vs EkkoTriumph - best Vayne rune vs EkkoLegend: Alacrity - best Vayne rune vs EkkoCoup de Grace - best Vayne rune vs Ekko
Domination rune tree - Vayne secondary runes vs EkkoDomination
Sudden Impact - best Vayne rune vs EkkoTreasure Hunter - best Vayne rune vs Ekko
100.0% WR

Running Precision primary with Domination secondary allows Vayne to press their advantage against Ekko, amplifying the strengths that make this a favorable matchup.


Vayne matchup data for League of Legends patch 26.10. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
41.92%6256.086813,33341.1%42.5%
47.54%4486.079512,72644.6%49.8%
45.21%4386.083213,04042.6%47.3%
52.08%3616.079812,88147.3%55.5%
55.08%3546.184413,39054.5%55.5%
50.58%3425.778212,20548.3%52.4%
49.41%2556.383112,91146.2%52.2%
50.23%2136.491113,46346.4%53.5%
52.17%1616.187912,86549.3%54.6%
54.11%1466.183512,37349.3%58.7%
40.29%1395.876213,02641.1%39.8%
44.09%1276.079712,49741.8%45.8%
45.53%1236.083613,64451.1%42.1%
51.75%1146.595812,12950.0%53.1%
42.48%1136.274112,45149.1%36.2%
49.11%1126.080713,15650.0%48.3%
42.73%1105.662910,73935.3%49.1%
52.34%1076.586213,34847.8%55.7%
59.05%1056.488611,50147.9%68.4%
56.86%1025.991411,30959.1%55.2%
34.12%855.757710,47122.2%42.9%
46.99%836.281112,47544.2%50.0%
44.44%815.988713,34034.5%50.0%
45.68%815.979412,79034.2%55.8%
57.14%706.080811,87960.0%54.3%
44.29%706.284013,07946.1%43.2%
51.43%706.090011,65360.6%43.2%
46.38%696.283912,37145.5%47.2%
57.14%636.372710,33954.8%59.4%
55.56%636.61,10113,01644.0%63.2%
47.27%555.689110,82043.3%52.0%
47.17%536.11,29311,98144.0%50.0%
59.62%525.71,14212,39755.0%62.5%
42.00%506.394412,46360.0%30.0%
58.33%487.085312,02354.5%61.5%
45.83%486.193112,33035.7%50.0%
48.94%476.786411,04546.1%52.4%
51.11%456.080611,13057.1%45.8%
48.78%416.196312,04750.0%48.1%
50.00%405.887111,46344.4%54.5%
57.50%406.21,09714,06850.0%62.5%
57.89%385.980111,87960.0%56.5%
55.56%366.496613,12264.7%47.4%
34.29%355.974611,79146.1%27.3%
45.45%336.290712,80535.3%56.3%
48.48%335.982212,72641.7%52.4%
57.58%336.61,08313,66278.6%42.1%
53.13%326.276113,13645.5%57.1%
68.75%326.786012,02581.3%56.3%
54.84%316.193013,08140.0%68.8%
45.16%316.11,04212,10138.5%50.0%
64.52%316.390211,91462.5%66.7%
50.00%306.584011,79955.6%41.7%
50.00%306.587813,11753.9%47.1%
53.57%285.380711,85458.3%50.0%
64.29%286.295812,67650.0%72.2%
51.85%275.886310,39962.5%36.4%
66.67%274.489911,32862.5%72.7%
37.04%275.471410,24823.1%50.0%
57.69%266.388712,85663.6%53.3%
61.54%266.495111,95670.0%56.3%
60.00%256.589910,03543.8%88.9%
76.00%255.866511,16883.3%69.2%
43.48%235.278011,86755.6%35.7%
59.09%226.381612,43166.7%53.9%
52.38%215.490212,33328.6%64.3%
52.38%216.11,03813,81357.1%50.0%
57.14%216.273111,72554.5%60.0%
57.14%216.489712,48645.5%70.0%
20.00%205.971811,38410.0%30.0%
57.89%196.279313,25060.0%57.1%
57.89%196.690012,87850.0%61.5%
57.89%195.782813,10950.0%61.5%
42.11%196.091613,24833.3%43.8%
55.56%185.377211,11636.4%85.7%
44.44%186.185413,60516.7%58.3%
47.06%175.970010,86142.9%50.0%
47.06%175.26669,14730.0%71.4%
35.29%176.076111,77428.6%40.0%
50.00%164.663410,34244.4%57.1%
56.25%166.188414,21550.0%60.0%
43.75%166.398911,25050.0%40.0%
56.25%166.391714,91760.0%54.5%
26.67%156.088211,23833.3%22.2%
33.33%156.21,08210,63922.2%50.0%
69.23%133.298712,45962.5%80.0%
38.46%136.27449,96928.6%50.0%
50.00%126.090913,25833.3%55.6%
58.33%124.91,10413,26366.7%50.0%
58.33%126.91,16413,46766.7%55.6%
58.33%125.997814,9320.0%70.0%
36.36%116.06429,77550.0%20.0%
54.55%117.098114,32180.0%33.3%
60.00%106.568311,51050.0%66.7%
50.00%105.370510,52928.6%100.0%
70.00%106.193910,57071.4%66.7%
50.00%104.080211,34640.0%60.0%
60.00%106.91,05713,02580.0%40.0%
33.33%95.61,04712,1310.0%37.5%
33.33%92.572112,37620.0%50.0%
55.56%94.91,04914,74250.0%57.1%
44.44%92.580012,70320.0%75.0%
62.50%82.685511,71850.0%75.0%
50.00%86.28089,79750.0%50.0%
75.00%85.685713,26366.7%80.0%
37.50%86.478211,30675.0%0.0%
57.14%74.674914,4010.0%66.7%
71.43%73.81,13515,166100.0%66.7%
14.29%76.577612,58625.0%0.0%
28.57%73.654511,51750.0%20.0%
42.86%76.79849,41050.0%33.3%
50.00%62.81,02610,03233.3%66.7%
33.33%65.863011,692100.0%20.0%
66.67%66.31,12813,31050.0%75.0%
50.00%61.581212,00650.0%50.0%
66.67%66.91,18714,237100.0%33.3%
40.00%54.794114,64550.0%33.3%
60.00%52.45278,33033.3%100.0%
80.00%52.41,03614,100100.0%75.0%
80.00%56.269210,724100.0%50.0%

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Vayne vs Ekko - Frequently Asked Questions

How does Vayne do against Ekko in League of Legends?

Vayne wins the Vayne vs Ekko matchup with a 55.6% win rate compared to Ekko's 44.4%, a 11.1 percentage point difference. This data is based on 9 recent ranked games in patch 26.10.

How does Vayne do against Ekko in the early game?

In the early game, Vayne has the advantage against Ekko with a 50.0% win rate versus 50.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Ekko in the late game?

In the late game, Vayne takes over the Vayne vs Ekko matchup with a 57.1% win rate compared to 42.9%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Ekko matchup?

Vayne wins the matchup against Ekko with a 55.6% win rate in League of Legends patch 26.10. The 11.1 percentage point advantage means Vayne is significantly favored in this lane matchup based on 9 games analyzed.

What is the best Vayne build against Ekko?

The best Vayne build against Ekko includes Essence Reaver, Blade of The Ruined King, Experimental Hexplate with Immortal Path. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Ekko?

The best Vayne runes against Ekko use the Precision primary tree with Domination secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Ekko matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Ekko?

Yes, Vayne has a favorable matchup against Ekko with a 55.6% win rate. Vayne strongly counters Ekko in lane based on current patch 26.10 data.

How do I play Vayne against Ekko?

When playing Vayne against Ekko, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.