Vayne - League of Legends Champion
Win Rate
50.5%
Pick Rate
4.6%

Vaynevs Ekko

BMarksmanAssassin
Patch26.4
Matches1,089,240
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 5, 2026
MethodologyData Methodology

Vayne vs Ekko is a decisive matchup in LoL patch 26.4. Ekko wins with a 60.0% win rate (+20.0%) over Vayne based on 5 games. Vayne wins the early laning phase while Ekko scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Ekko matchup.

Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Ekko - 40.0% win rateEkko(40.0%)
Vayne - 40.0% win rate in this matchup
Vayne
40.0% WR
VS
Ekko vs Vayne matchup - 60.0% win rate
Ekko
60.0% WR

Who Wins the Vayne vs Ekko Matchup?

Ekko wins the Vayne vs Ekko matchup
Winner
Ekko
Matches: 5
40.0%
Win Rate
60.0%
3.1
CS / min
2.8
1,070
DMG / min
865
12,851
Gold / game
12,857
328
Heal / min
459
501
DMG Mitigated / min
835
0.6
CC / min
0.7
50.0%
Early Game WR
50.0%
0.0%
Late Game WR
100.0%

Vayne vs Ekko Matchup Summary

The Vayne vs Ekko matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Ekko wins with a 60.0% win rate compared to Vayne's 40.0%, giving Ekko a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Ekko outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Ekko reaches their power spikes, while Ekko should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Ekko leads by 465 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Ekko has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Ekko overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Ekko Laning Phase Breakdown

Ekko wins the laning phase against Vayne in League of Legends

Ekko is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Ekko holds advantages in gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
3.1Vayne
2.8Ekko
Vayne and Ekko farm at nearly identical rates in this matchup, with only a 0.3 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
1,070Vayne
865Ekko
Vayne heavily out-damages Ekko by 205 DMG/min, dominating both short trades and all-in fights. Ekko should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
12,851Vayne
12,857Ekko
Vayne and Ekko generate nearly equal gold per game, with just a 6 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.6Vayne
0.7Ekko
Both Vayne and Ekko provide similar amounts of crowd control (0.0s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
829Vayne
1,294Ekko
Ekko vastly out-sustains Vayne, healing and mitigating 465 more damage per minute. This massive durability gap means Ekko can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Ekko

Berserker's Greaves is the optimal boots choice against Ekko, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Ekko are Essence Reaver, Blade of The Ruined King and Stormrazor. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Ekko matchup.

Early Game vs Late Game

Early Game
Vayne
50.0%
+0.0% advantage
Vayne early game win rateVayne50.0%
Ekko early game win rateEkko50.0%
Late Game
Ekko
100.0%
+100.0% advantage
Vayne late game win rateVayne0.0%
Ekko late game win rateEkko100.0%

The early game (first 15 minutes) is a toss-up between Vayne and Ekko, with Vayne holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Ekko is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Vayne. Extended games heavily favor Ekko, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Vayne has the edge early, but Ekko gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Vayne Runes Against Ekko

Precision rune tree - Vayne primary runes vs EkkoPrecision
Press the Attack - best Vayne rune vs EkkoTriumph - best Vayne rune vs EkkoLegend: Alacrity - best Vayne rune vs EkkoCoup de Grace - best Vayne rune vs Ekko
Domination rune tree - Vayne secondary runes vs EkkoDomination
Taste of Blood - best Vayne rune vs EkkoTreasure Hunter - best Vayne rune vs Ekko
100.0% WR

The Precision and Domination rune setup gives Vayne the best tools to compete against Ekko in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Vayne matchup data for League of Legends patch 26.4. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.4
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
50.82%7326.180313,25851.6%50.3%
50.47%6435.981913,61051.8%49.5%
50.16%6266.386013,31448.9%51.4%
53.35%5296.186813,34852.2%54.2%
49.25%4756.590413,93644.6%53.5%
56.36%4026.491813,99152.9%59.4%
46.70%3956.080213,25141.1%51.1%
52.87%3546.492214,14751.2%53.9%
48.04%2826.084313,50556.5%42.2%
51.29%2716.587013,47253.7%49.3%
52.54%2396.288813,13952.5%52.6%
54.25%2126.591714,46558.5%51.5%
51.26%2006.283713,33657.7%44.2%
55.00%2006.182113,16149.5%60.0%
47.40%1926.389113,42449.0%45.8%
55.56%1816.085813,65358.1%53.8%
49.11%1706.287313,70246.5%51.0%
49.63%1355.985414,04346.3%51.9%
55.65%1156.190213,63258.8%53.1%
53.15%1116.084211,67052.9%53.3%
57.41%1096.590812,76754.2%60.0%
50.00%1066.283813,92548.7%50.8%
60.20%996.199412,48161.9%58.9%
54.74%965.81,03114,05643.6%62.5%
51.09%926.191413,61256.1%47.1%
45.65%926.384513,98043.6%47.2%
51.65%916.489314,00447.4%54.7%
50.59%876.394912,10352.9%49.0%
45.88%866.185913,54056.8%37.5%
45.12%835.760311,33933.3%54.4%
46.15%786.089711,41528.9%62.5%
44.16%776.31,39112,48136.7%48.9%
39.47%776.288514,18028.0%45.1%
53.73%685.564011,62826.1%68.2%
45.45%666.696914,14246.9%44.1%
49.23%666.31,02112,93252.0%47.5%
53.13%646.01,00511,45151.5%54.8%
45.31%646.285813,54544.4%46.0%
50.00%646.398712,06041.4%57.1%
59.32%596.199711,68457.1%61.3%
50.00%566.591913,45255.6%44.8%
50.00%546.494912,10040.0%55.9%
57.14%496.384312,07754.2%60.0%
53.06%496.494512,15460.9%46.1%
47.92%486.380412,12534.8%60.0%
46.81%486.597012,45347.6%46.1%
51.06%476.592611,29546.1%57.1%
51.11%457.299813,30647.6%54.2%
32.56%435.87009,81520.7%57.1%
69.77%436.890315,25571.4%69.0%
51.16%436.198611,82545.8%57.9%
52.38%426.687712,78847.6%57.1%
55.00%406.097011,81355.6%54.5%
55.00%405.891414,58447.4%61.9%
58.97%396.081012,83146.7%66.7%
48.65%386.084011,26447.6%50.0%
43.24%375.782511,62740.0%47.1%
45.71%356.094612,63827.3%54.2%
33.33%336.588813,38920.0%39.1%
48.48%336.072813,05940.0%55.6%
48.39%326.292713,03146.1%50.0%
54.84%316.182311,63250.0%58.8%
46.67%306.076812,08346.1%47.1%
63.33%306.488612,70272.7%57.9%
44.44%275.495212,11458.3%33.3%
50.00%266.588911,51646.1%53.9%
61.54%266.81,08714,27762.5%61.1%
46.15%265.284913,31170.0%31.3%
50.00%266.579212,81066.7%35.7%
46.15%266.61,14412,90646.7%45.5%
50.00%266.81,09014,26366.7%41.2%
50.00%246.188512,72954.5%46.1%
40.91%236.587614,59940.0%41.7%
60.87%236.390914,13163.6%58.3%
52.38%225.586013,67055.6%50.0%
42.86%216.584511,53433.3%55.6%
50.00%206.073810,24154.5%44.4%
63.16%196.31,06115,663100.0%53.3%
52.63%195.983912,95142.9%58.3%
52.94%176.01,02012,52340.0%71.4%
43.75%165.762410,93325.0%62.5%
62.50%166.881711,30363.6%60.0%
26.67%156.56669,61722.2%33.3%
40.00%154.089712,23157.1%25.0%
35.71%146.463711,28033.3%40.0%
42.86%146.984611,76328.6%57.1%
42.86%146.392511,74442.9%42.9%
38.46%134.782713,52216.7%57.1%
46.15%135.896112,41620.0%62.5%
46.15%135.998214,62342.9%50.0%
50.00%125.789715,26533.3%55.6%
41.67%126.797615,74340.0%42.9%
58.33%124.583212,19950.0%62.5%
58.33%125.978111,83020.0%85.7%
41.67%124.476311,16450.0%25.0%
54.55%112.91,05515,23950.0%57.1%
36.36%116.675013,0070.0%44.4%
45.45%114.280712,51350.0%40.0%
36.36%116.390412,25950.0%28.6%
22.22%104.26589,34814.3%50.0%
50.00%105.91,13212,11860.0%40.0%
40.00%104.877312,40933.3%50.0%
33.33%93.473212,8440.0%42.9%
44.44%94.469512,82450.0%40.0%
62.50%86.066012,870100.0%50.0%
25.00%84.275811,7450.0%66.7%
62.50%85.889913,4690.0%100.0%
14.29%76.01,05415,4820.0%16.7%
71.43%76.684915,13250.0%80.0%
71.43%74.483412,500100.0%50.0%
66.67%66.778713,85750.0%75.0%
33.33%66.975311,851100.0%0.0%
50.00%65.195712,1060.0%60.0%
50.00%66.589810,84275.0%0.0%
33.33%61.280811,0650.0%100.0%
50.00%64.077515,502100.0%40.0%
60.00%56.31,18019,8650.0%60.0%
25.00%52.456711,13350.0%0.0%
40.00%56.385511,5310.0%66.7%
60.00%56.41,09915,068100.0%33.3%
40.00%55.187711,5370.0%100.0%
40.00%53.11,07012,85150.0%0.0%
40.00%52.770614,2870.0%50.0%
0.00%56.078112,1500.0%0.0%
60.00%56.91,19213,2620.0%100.0%
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Vayne vs Ekko - Frequently Asked Questions

How does Vayne do against Ekko in League of Legends?

Ekko wins the Vayne vs Ekko matchup with a 60.0% win rate compared to Vayne's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.4.

How does Vayne do against Ekko in the early game?

In the early game, Vayne has the advantage against Ekko with a 50.0% win rate versus 50.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Ekko in the late game?

In the late game, Ekko takes over the Vayne vs Ekko matchup with a 100.0% win rate compared to 0.0%. Ekko scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Ekko matchup?

Ekko wins the matchup against Vayne with a 60.0% win rate in League of Legends patch 26.4. The 20.0 percentage point advantage means Ekko is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Vayne build against Ekko?

The best Vayne build against Ekko includes Essence Reaver, Blade of The Ruined King, Stormrazor with Berserker's Greaves. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Ekko?

The best Vayne runes against Ekko use the Precision primary tree with Domination secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Ekko matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Ekko?

No, Vayne struggles against Ekko with only a 40.0% win rate. Ekko has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Ekko's lead.

How do I play Vayne against Ekko?

When playing Vayne against Ekko, play cautiously and avoid Ekko's power spikes. Look for jungle assistance and team-dependent plays since Ekko has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.