Vayne - League of Legends Champion
Win Rate
50.0%
Pick Rate
5.2%

Vaynevs Lillia

BMarksmanAssassin
Patch26.10
Matches1,009,027
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 18, 2026
MethodologyData Methodology

Vayne vs Lillia is a very close matchup in LoL patch 26.10. Vayne wins with a 50.0% win rate (+0.0%) over Lillia based on 6 games. Vayne wins the early laning phase while Lillia scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Lillia matchup.

Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lillia - 50.0% win rateLillia(50.0%)
Vayne - 50.0% win rate in this matchup
Vayne
50.0% WR
VS
Lillia vs Vayne matchup - 50.0% win rate
Lillia
50.0% WR

Who Wins the Vayne vs Lillia Matchup?

Vayne wins the Vayne vs Lillia matchup
Winner
Vayne
Matches: 6
50.0%
Win Rate
50.0%
3.2
CS / min
2.5
1,128
DMG / min
679
17,178
Gold / game
12,925
306
Heal / min
521
560
DMG Mitigated / min
836
0.5
CC / min
0.9
100.0%
Early Game WR
0.0%
40.0%
Late Game WR
60.0%

Vayne vs Lillia Matchup Summary

The Vayne vs Lillia matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Vayne wins with a 50.0% win rate compared to Lillia's 50.0%, giving Vayne a 0.0 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Lillia outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Lillia reaches their power spikes, while Lillia should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Lillia leads by 0.4s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a statistical edge, but the margin is close enough that respecting Lillia's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Lillia Laning Phase Breakdown

Vayne wins the laning phase against Lillia in League of Legends

Vayne is favored during the laning phase against Lillia, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
3.2Vayne
2.5Lillia
Vayne edges out Lillia by 0.7 CS per minute — a moderate farming advantage that adds up to roughly 10 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Vayne.
Damage
1,128Vayne
679Lillia
Vayne heavily out-damages Lillia by 449 DMG/min, dominating both short trades and all-in fights. Lillia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
17,178Vayne
12,925Lillia
Vayne generates a commanding 4,253 more gold per game than Lillia. This substantial economic advantage means Vayne consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Lillia should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.5Vayne
0.9Lillia
Lillia provides 0.4 seconds more crowd control per minute than Vayne, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Lillia coordinate with their jungler and control the pace of skirmishes.
Sustain
866Vayne
1,357Lillia
Lillia vastly out-sustains Vayne, healing and mitigating 491 more damage per minute. This massive durability gap means Lillia can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Lillia

Berserker's Greaves is the optimal boots choice against Lillia, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Lillia are Essence Reaver, Stormrazor and Wit's End. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Lillia matchup.

Early Game vs Late Game

Early Game
Vayne
100.0%
+100.0% advantage
Vayne early game win rateVayne100.0%
Lillia early game win rateLillia0.0%
Late Game
Lillia
60.0%
+20.0% advantage
Vayne late game win rateVayne40.0%
Lillia late game win rateLillia60.0%

Vayne dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Lillia. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Lillia is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Vayne. Extended games heavily favor Lillia, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Vayne must aggressively press their early advantage and close out the game before Lillia reaches their scaling breakpoints. If Lillia survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Vayne Runes Against Lillia

Precision rune tree - Vayne primary runes vs LilliaPrecision
Press the Attack - best Vayne rune vs LilliaTriumph - best Vayne rune vs LilliaLegend: Alacrity - best Vayne rune vs LilliaCut Down - best Vayne rune vs Lillia
Inspiration rune tree - Vayne secondary runes vs LilliaInspiration
Cash Back - best Vayne rune vs LilliaTriple Tonic - best Vayne rune vs Lillia
100.0% WR

The Precision primary with Inspiration secondary combination helps Vayne maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Lillia.


Vayne matchup data for League of Legends patch 26.10. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
42.79%8886.187313,42543.8%42.2%
45.78%6516.183212,92942.2%49.0%
48.13%6426.079912,92043.9%51.2%
53.42%5266.184213,10753.0%53.8%
51.10%5016.080012,97847.5%53.5%
50.31%4855.876912,32347.6%52.7%
49.35%3836.384512,93348.2%50.2%
53.27%3066.391613,43450.7%55.4%
53.62%2356.086412,64049.6%57.4%
54.59%2076.183412,66748.9%59.3%
47.29%2035.980413,16448.8%46.2%
48.15%1896.185513,55151.4%46.2%
49.11%1696.084412,90648.1%50.0%
45.51%1676.081812,76943.1%47.4%
46.99%1666.277612,77449.4%44.9%
48.77%1626.595411,99745.2%51.7%
39.75%1615.862010,95728.8%48.9%
50.63%1606.589913,74644.8%54.8%
59.73%1496.489911,99949.2%67.4%
59.12%1376.091811,82360.3%58.2%
46.67%1356.080513,26436.4%53.8%
31.34%1345.556510,41421.4%38.5%
45.08%1226.281212,58444.4%45.8%
42.02%1196.084812,89935.3%47.1%
40.71%1136.384313,35245.5%37.7%
49.54%1096.387912,55455.8%43.9%
57.14%1056.183812,22757.1%57.1%
47.52%1015.992311,20553.1%42.3%
58.62%876.172810,51751.2%65.2%
54.02%876.51,11012,89542.1%63.3%
46.34%825.688511,27345.0%47.6%
48.72%786.11,30512,21745.5%51.1%
51.35%746.079811,63060.0%45.5%
54.29%705.71,11912,77750.0%56.5%
43.48%696.193512,09237.5%46.7%
50.00%686.496012,25767.7%35.1%
58.82%686.985811,92157.6%60.0%
52.31%656.691911,61948.4%55.9%
51.72%586.31,00412,69160.9%45.7%
47.17%536.482911,66048.4%45.5%
48.08%526.277812,96940.9%53.3%
65.38%526.190112,18565.2%65.5%
50.00%526.299612,61152.9%48.6%
49.02%516.089111,77545.5%51.7%
52.94%515.878913,08645.0%58.1%
52.00%506.11,03113,73050.0%53.6%
58.33%485.975411,85658.8%58.1%
52.08%486.21,07512,35247.4%55.2%
58.70%466.492212,82560.9%56.5%
45.65%466.187812,27036.0%57.1%
59.09%445.988513,40042.1%72.0%
65.91%446.588712,62471.4%60.9%
41.86%435.976712,17650.0%37.9%
50.00%425.681411,71250.0%50.0%
65.85%414.788011,77569.6%61.1%
60.00%406.297511,57856.3%62.5%
48.72%395.582212,49557.1%44.0%
55.26%386.385312,78562.5%50.0%
50.00%386.586012,42650.0%50.0%
50.00%366.085410,98050.0%50.0%
62.86%356.395612,63158.3%65.2%
45.71%355.678510,66629.4%61.1%
68.57%355.971011,76068.8%68.4%
45.45%334.982512,05018.2%59.1%
51.61%316.384413,16546.1%55.6%
54.84%316.479312,36658.3%52.6%
56.67%306.492610,44042.1%81.8%
60.00%306.082813,52050.0%63.6%
37.93%296.297813,97050.0%33.3%
53.57%285.185912,05146.1%60.0%
50.00%286.387512,48542.9%57.1%
35.71%286.173810,27726.7%46.1%
51.85%275.985614,50250.0%52.6%
37.04%276.591710,35928.6%46.1%
48.15%275.676812,78136.4%56.3%
50.00%264.770511,60150.0%50.0%
34.62%265.986911,15830.8%38.5%
46.15%266.188412,59760.0%42.9%
44.00%255.46408,87031.3%66.7%
68.00%256.588012,13066.7%68.8%
45.83%245.873110,71650.0%41.7%
52.17%236.184913,28733.3%64.3%
39.13%236.090710,46630.8%50.0%
30.43%235.872811,24718.2%41.7%
57.14%216.287513,99137.5%69.2%
57.14%213.496513,01458.3%55.6%
60.00%206.31,04112,75760.0%60.0%
35.29%175.973211,73928.6%40.0%
56.25%166.081713,55725.0%66.7%
62.50%164.81,11613,76050.0%75.0%
53.33%156.099014,4700.0%72.7%
60.00%156.098911,79762.5%57.1%
33.33%156.483412,17566.7%11.1%
42.86%146.166210,38250.0%33.3%
57.14%146.895614,50483.3%37.5%
42.86%144.975114,0450.0%46.1%
50.00%146.51,11113,81366.7%37.5%
50.00%145.81,02411,71466.7%45.5%
38.46%134.063411,63550.0%33.3%
53.85%136.085511,23837.5%80.0%
50.00%126.470210,98140.0%57.1%
33.33%126.386213,28920.0%42.9%
66.67%122.484313,17450.0%75.0%
41.67%123.980212,00340.0%42.9%
54.55%112.083310,53842.9%75.0%
45.45%114.874010,87828.6%75.0%
54.55%115.097314,27966.7%50.0%
36.36%116.693310,38360.0%16.7%
54.55%115.51,10012,54325.0%71.4%
70.00%105.690313,78850.0%83.3%
50.00%102.874712,54320.0%80.0%
77.78%97.01,05114,103100.0%60.0%
55.56%94.31,00013,94133.3%66.7%
44.44%92.988115,885100.0%37.5%
55.56%93.585112,68933.3%66.7%
62.50%81.777112,33966.7%60.0%
50.00%85.477711,605100.0%20.0%
37.50%82.073912,73325.0%50.0%
57.14%72.25918,26750.0%66.7%
28.57%75.769712,250100.0%16.7%
57.14%71.065913,56650.0%66.7%
57.14%72.41,29615,60766.7%50.0%
50.00%64.399614,68650.0%50.0%
16.67%66.87488,36520.0%0.0%
50.00%63.21,12817,178100.0%40.0%
33.33%66.28279,58025.0%50.0%
60.00%56.163311,23366.7%50.0%
80.00%55.11,03613,35450.0%100.0%
20.00%57.179310,59033.3%0.0%
80.00%54.783512,087100.0%66.7%
60.00%53.885011,66050.0%66.7%
80.00%52.41,03614,100100.0%75.0%

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Vayne vs Lillia - Frequently Asked Questions

How does Vayne do against Lillia in League of Legends?

Vayne wins the Vayne vs Lillia matchup with a 50.0% win rate compared to Lillia's 50.0%, a 0.0 percentage point difference. This data is based on 6 recent ranked games in patch 26.10.

How does Vayne do against Lillia in the early game?

In the early game, Vayne has the advantage against Lillia with a 100.0% win rate versus 0.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Lillia in the late game?

In the late game, Lillia takes over the Vayne vs Lillia matchup with a 60.0% win rate compared to 40.0%. Lillia scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Lillia matchup?

Vayne wins the matchup against Lillia with a 50.0% win rate in League of Legends patch 26.10. The 0.0 percentage point advantage means Vayne is slightly favored in this lane matchup based on 6 games analyzed.

What is the best Vayne build against Lillia?

The best Vayne build against Lillia includes Essence Reaver, Stormrazor, Wit's End with Berserker's Greaves. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Lillia?

The best Vayne runes against Lillia use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Lillia matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Lillia?

Yes, Vayne has a favorable matchup against Lillia with a 50.0% win rate. Vayne slightly edges out Lillia in lane based on current patch 26.10 data.

How do I play Vayne against Lillia?

When playing Vayne against Lillia, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.