
Vaynevs Kha'Zix
Vayne vs Kha'Zix is a decisive matchup in LoL patch 26.10. Vayne wins with a 57.1% win rate (+14.3%) over Kha'Zix based on 7 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Kha'Zix matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Vayne vs Kha'Zix Matchup?

Vayne vs Kha'Zix Matchup Summary
The Vayne vs Kha'Zix matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Vayne wins with a 57.1% win rate compared to Kha'Zix's 42.9%, giving Vayne a 14.3 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Kha'Zix players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Vayne leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Kha'Zix and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Kha'Zix away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Kha'Zix Laning Phase Breakdown
Vayne is favored during the laning phase against Kha'Zix, winning 4 out of 5 key stat categories. Vayne holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.
Best Vayne Build Against Kha'Zix
Berserker's Greaves is the optimal boots choice against Kha'Zix, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Kha'Zix are Terminus, Blade of The Ruined King and Guinsoo's Rageblade. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Kha'Zix matchup.
Early Game vs Late Game
The early game (first 15 minutes) is a toss-up between Vayne and Kha'Zix, with Vayne holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.
Vayne is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Kha'Zix. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.
Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Kha'Zix players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Vayne Runes Against Kha'Zix
Running Precision primary with Inspiration secondary allows Vayne to press their advantage against Kha'Zix, amplifying the strengths that make this a favorable matchup.
Vayne matchup data for League of Legends patch 26.10. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 42.79% | 888 | 6.1 | 873 | 13,425 | 43.8% | 42.2% | |
| 45.78% | 651 | 6.1 | 832 | 12,929 | 42.2% | 49.0% | |
| 48.13% | 642 | 6.0 | 799 | 12,920 | 43.9% | 51.2% | |
| 53.42% | 526 | 6.1 | 842 | 13,107 | 53.0% | 53.8% | |
| 51.10% | 501 | 6.0 | 800 | 12,978 | 47.5% | 53.5% | |
| 50.31% | 485 | 5.8 | 769 | 12,323 | 47.6% | 52.7% | |
| 49.35% | 383 | 6.3 | 845 | 12,933 | 48.2% | 50.2% | |
| 53.27% | 306 | 6.3 | 916 | 13,434 | 50.7% | 55.4% | |
| 53.62% | 235 | 6.0 | 864 | 12,640 | 49.6% | 57.4% | |
| 54.59% | 207 | 6.1 | 834 | 12,667 | 48.9% | 59.3% | |
| 47.29% | 203 | 5.9 | 804 | 13,164 | 48.8% | 46.2% | |
| 48.15% | 189 | 6.1 | 855 | 13,551 | 51.4% | 46.2% | |
| 49.11% | 169 | 6.0 | 844 | 12,906 | 48.1% | 50.0% | |
| 45.51% | 167 | 6.0 | 818 | 12,769 | 43.1% | 47.4% | |
| 46.99% | 166 | 6.2 | 776 | 12,774 | 49.4% | 44.9% | |
| 48.77% | 162 | 6.5 | 954 | 11,997 | 45.2% | 51.7% | |
| 39.75% | 161 | 5.8 | 620 | 10,957 | 28.8% | 48.9% | |
| 50.63% | 160 | 6.5 | 899 | 13,746 | 44.8% | 54.8% | |
| 59.73% | 149 | 6.4 | 899 | 11,999 | 49.2% | 67.4% | |
| 59.12% | 137 | 6.0 | 918 | 11,823 | 60.3% | 58.2% | |
| 46.67% | 135 | 6.0 | 805 | 13,264 | 36.4% | 53.8% | |
| 31.34% | 134 | 5.5 | 565 | 10,414 | 21.4% | 38.5% | |
| 45.08% | 122 | 6.2 | 812 | 12,584 | 44.4% | 45.8% | |
| 42.02% | 119 | 6.0 | 848 | 12,899 | 35.3% | 47.1% | |
| 40.71% | 113 | 6.3 | 843 | 13,352 | 45.5% | 37.7% | |
| 49.54% | 109 | 6.3 | 879 | 12,554 | 55.8% | 43.9% | |
| 57.14% | 105 | 6.1 | 838 | 12,227 | 57.1% | 57.1% | |
| 47.52% | 101 | 5.9 | 923 | 11,205 | 53.1% | 42.3% | |
| 58.62% | 87 | 6.1 | 728 | 10,517 | 51.2% | 65.2% | |
| 54.02% | 87 | 6.5 | 1,110 | 12,895 | 42.1% | 63.3% | |
| 46.34% | 82 | 5.6 | 885 | 11,273 | 45.0% | 47.6% | |
| 48.72% | 78 | 6.1 | 1,305 | 12,217 | 45.5% | 51.1% | |
| 51.35% | 74 | 6.0 | 798 | 11,630 | 60.0% | 45.5% | |
| 54.29% | 70 | 5.7 | 1,119 | 12,777 | 50.0% | 56.5% | |
| 43.48% | 69 | 6.1 | 935 | 12,092 | 37.5% | 46.7% | |
| 50.00% | 68 | 6.4 | 960 | 12,257 | 67.7% | 35.1% | |
| 58.82% | 68 | 6.9 | 858 | 11,921 | 57.6% | 60.0% | |
| 52.31% | 65 | 6.6 | 919 | 11,619 | 48.4% | 55.9% | |
| 51.72% | 58 | 6.3 | 1,004 | 12,691 | 60.9% | 45.7% | |
| 47.17% | 53 | 6.4 | 829 | 11,660 | 48.4% | 45.5% | |
| 48.08% | 52 | 6.2 | 778 | 12,969 | 40.9% | 53.3% | |
| 65.38% | 52 | 6.1 | 901 | 12,185 | 65.2% | 65.5% | |
| 50.00% | 52 | 6.2 | 996 | 12,611 | 52.9% | 48.6% | |
| 49.02% | 51 | 6.0 | 891 | 11,775 | 45.5% | 51.7% | |
| 52.94% | 51 | 5.8 | 789 | 13,086 | 45.0% | 58.1% | |
| 52.00% | 50 | 6.1 | 1,031 | 13,730 | 50.0% | 53.6% | |
| 58.33% | 48 | 5.9 | 754 | 11,856 | 58.8% | 58.1% | |
| 52.08% | 48 | 6.2 | 1,075 | 12,352 | 47.4% | 55.2% | |
| 58.70% | 46 | 6.4 | 922 | 12,825 | 60.9% | 56.5% | |
| 45.65% | 46 | 6.1 | 878 | 12,270 | 36.0% | 57.1% | |
| 59.09% | 44 | 5.9 | 885 | 13,400 | 42.1% | 72.0% | |
| 65.91% | 44 | 6.5 | 887 | 12,624 | 71.4% | 60.9% | |
| 41.86% | 43 | 5.9 | 767 | 12,176 | 50.0% | 37.9% | |
| 50.00% | 42 | 5.6 | 814 | 11,712 | 50.0% | 50.0% | |
| 65.85% | 41 | 4.7 | 880 | 11,775 | 69.6% | 61.1% | |
| 60.00% | 40 | 6.2 | 975 | 11,578 | 56.3% | 62.5% | |
| 48.72% | 39 | 5.5 | 822 | 12,495 | 57.1% | 44.0% | |
| 55.26% | 38 | 6.3 | 853 | 12,785 | 62.5% | 50.0% | |
| 50.00% | 38 | 6.5 | 860 | 12,426 | 50.0% | 50.0% | |
| 50.00% | 36 | 6.0 | 854 | 10,980 | 50.0% | 50.0% | |
| 62.86% | 35 | 6.3 | 956 | 12,631 | 58.3% | 65.2% | |
| 45.71% | 35 | 5.6 | 785 | 10,666 | 29.4% | 61.1% | |
| 68.57% | 35 | 5.9 | 710 | 11,760 | 68.8% | 68.4% | |
| 45.45% | 33 | 4.9 | 825 | 12,050 | 18.2% | 59.1% | |
| 51.61% | 31 | 6.3 | 844 | 13,165 | 46.1% | 55.6% | |
| 54.84% | 31 | 6.4 | 793 | 12,366 | 58.3% | 52.6% | |
| 56.67% | 30 | 6.4 | 926 | 10,440 | 42.1% | 81.8% | |
| 60.00% | 30 | 6.0 | 828 | 13,520 | 50.0% | 63.6% | |
| 37.93% | 29 | 6.2 | 978 | 13,970 | 50.0% | 33.3% | |
| 53.57% | 28 | 5.1 | 859 | 12,051 | 46.1% | 60.0% | |
| 50.00% | 28 | 6.3 | 875 | 12,485 | 42.9% | 57.1% | |
| 35.71% | 28 | 6.1 | 738 | 10,277 | 26.7% | 46.1% | |
| 51.85% | 27 | 5.9 | 856 | 14,502 | 50.0% | 52.6% | |
| 37.04% | 27 | 6.5 | 917 | 10,359 | 28.6% | 46.1% | |
| 48.15% | 27 | 5.6 | 768 | 12,781 | 36.4% | 56.3% | |
| 50.00% | 26 | 4.7 | 705 | 11,601 | 50.0% | 50.0% | |
| 34.62% | 26 | 5.9 | 869 | 11,158 | 30.8% | 38.5% | |
| 46.15% | 26 | 6.1 | 884 | 12,597 | 60.0% | 42.9% | |
| 44.00% | 25 | 5.4 | 640 | 8,870 | 31.3% | 66.7% | |
| 68.00% | 25 | 6.5 | 880 | 12,130 | 66.7% | 68.8% | |
| 45.83% | 24 | 5.8 | 731 | 10,716 | 50.0% | 41.7% | |
| 52.17% | 23 | 6.1 | 849 | 13,287 | 33.3% | 64.3% | |
| 39.13% | 23 | 6.0 | 907 | 10,466 | 30.8% | 50.0% | |
| 30.43% | 23 | 5.8 | 728 | 11,247 | 18.2% | 41.7% | |
| 57.14% | 21 | 6.2 | 875 | 13,991 | 37.5% | 69.2% | |
| 57.14% | 21 | 3.4 | 965 | 13,014 | 58.3% | 55.6% | |
| 60.00% | 20 | 6.3 | 1,041 | 12,757 | 60.0% | 60.0% | |
| 35.29% | 17 | 5.9 | 732 | 11,739 | 28.6% | 40.0% | |
| 56.25% | 16 | 6.0 | 817 | 13,557 | 25.0% | 66.7% | |
| 62.50% | 16 | 4.8 | 1,116 | 13,760 | 50.0% | 75.0% | |
| 53.33% | 15 | 6.0 | 990 | 14,470 | 0.0% | 72.7% | |
| 60.00% | 15 | 6.0 | 989 | 11,797 | 62.5% | 57.1% | |
| 33.33% | 15 | 6.4 | 834 | 12,175 | 66.7% | 11.1% | |
| 42.86% | 14 | 6.1 | 662 | 10,382 | 50.0% | 33.3% | |
| 57.14% | 14 | 6.8 | 956 | 14,504 | 83.3% | 37.5% | |
| 42.86% | 14 | 4.9 | 751 | 14,045 | 0.0% | 46.1% | |
| 50.00% | 14 | 6.5 | 1,111 | 13,813 | 66.7% | 37.5% | |
| 50.00% | 14 | 5.8 | 1,024 | 11,714 | 66.7% | 45.5% | |
| 38.46% | 13 | 4.0 | 634 | 11,635 | 50.0% | 33.3% | |
| 53.85% | 13 | 6.0 | 855 | 11,238 | 37.5% | 80.0% | |
| 50.00% | 12 | 6.4 | 702 | 10,981 | 40.0% | 57.1% | |
| 33.33% | 12 | 6.3 | 862 | 13,289 | 20.0% | 42.9% | |
| 66.67% | 12 | 2.4 | 843 | 13,174 | 50.0% | 75.0% | |
| 41.67% | 12 | 3.9 | 802 | 12,003 | 40.0% | 42.9% | |
| 54.55% | 11 | 2.0 | 833 | 10,538 | 42.9% | 75.0% | |
| 45.45% | 11 | 4.8 | 740 | 10,878 | 28.6% | 75.0% | |
| 54.55% | 11 | 5.0 | 973 | 14,279 | 66.7% | 50.0% | |
| 36.36% | 11 | 6.6 | 933 | 10,383 | 60.0% | 16.7% | |
| 54.55% | 11 | 5.5 | 1,100 | 12,543 | 25.0% | 71.4% | |
| 70.00% | 10 | 5.6 | 903 | 13,788 | 50.0% | 83.3% | |
| 50.00% | 10 | 2.8 | 747 | 12,543 | 20.0% | 80.0% | |
| 77.78% | 9 | 7.0 | 1,051 | 14,103 | 100.0% | 60.0% | |
| 55.56% | 9 | 4.3 | 1,000 | 13,941 | 33.3% | 66.7% | |
| 44.44% | 9 | 2.9 | 881 | 15,885 | 100.0% | 37.5% | |
| 55.56% | 9 | 3.5 | 851 | 12,689 | 33.3% | 66.7% | |
| 62.50% | 8 | 1.7 | 771 | 12,339 | 66.7% | 60.0% | |
| 50.00% | 8 | 5.4 | 777 | 11,605 | 100.0% | 20.0% | |
| 37.50% | 8 | 2.0 | 739 | 12,733 | 25.0% | 50.0% | |
| 57.14% | 7 | 2.2 | 591 | 8,267 | 50.0% | 66.7% | |
| 28.57% | 7 | 5.7 | 697 | 12,250 | 100.0% | 16.7% | |
| 57.14% | 7 | 1.0 | 659 | 13,566 | 50.0% | 66.7% | |
| 57.14% | 7 | 2.4 | 1,296 | 15,607 | 66.7% | 50.0% | |
| 50.00% | 6 | 4.3 | 996 | 14,686 | 50.0% | 50.0% | |
| 16.67% | 6 | 6.8 | 748 | 8,365 | 20.0% | 0.0% | |
| 50.00% | 6 | 3.2 | 1,128 | 17,178 | 100.0% | 40.0% | |
| 33.33% | 6 | 6.2 | 827 | 9,580 | 25.0% | 50.0% | |
| 60.00% | 5 | 6.1 | 633 | 11,233 | 66.7% | 50.0% | |
| 80.00% | 5 | 5.1 | 1,036 | 13,354 | 50.0% | 100.0% | |
| 20.00% | 5 | 7.1 | 793 | 10,590 | 33.3% | 0.0% | |
| 80.00% | 5 | 4.7 | 835 | 12,087 | 100.0% | 66.7% | |
| 60.00% | 5 | 3.8 | 850 | 11,660 | 50.0% | 66.7% | |
| 80.00% | 5 | 2.4 | 1,036 | 14,100 | 100.0% | 75.0% | |
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Vayne vs Kha'Zix - Frequently Asked Questions
How does Vayne do against Kha'Zix in League of Legends?
Vayne wins the Vayne vs Kha'Zix matchup with a 57.1% win rate compared to Kha'Zix's 42.9%, a 14.3 percentage point difference. This data is based on 7 recent ranked games in patch 26.10.
How does Vayne do against Kha'Zix in the early game?
In the early game, Vayne has the advantage against Kha'Zix with a 50.0% win rate versus 50.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Kha'Zix in the late game?
In the late game, Vayne takes over the Vayne vs Kha'Zix matchup with a 66.7% win rate compared to 33.3%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Kha'Zix matchup?
Vayne wins the matchup against Kha'Zix with a 57.1% win rate in League of Legends patch 26.10. The 14.3 percentage point advantage means Vayne is significantly favored in this lane matchup based on 7 games analyzed.
What is the best Vayne build against Kha'Zix?
The best Vayne build against Kha'Zix includes Terminus, Blade of The Ruined King, Guinsoo's Rageblade with Berserker's Greaves. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Kha'Zix?
The best Vayne runes against Kha'Zix use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Kha'Zix matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Kha'Zix?
Yes, Vayne has a favorable matchup against Kha'Zix with a 57.1% win rate. Vayne strongly counters Kha'Zix in lane based on current patch 26.10 data.
How do I play Vayne against Kha'Zix?
When playing Vayne against Kha'Zix, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.
