Slay the Spire 2 Regent Relic Tier List

S-tier is led by Fiddle, which dominates the meta with a 100.0% win rate on a 0.6% pick rate. They are followed by Tri-Boomerang (100.0%), Lunar Pastry (100.0%), Glitter (100.0%), Neow's Talisman (100.0%), Mr. Struggles (100.0%), Looming Fruit (100.0%), and Jewelry Box (100.0%). The remaining 23 relics in this tier average a 80.4% win rate. These relics define the current meta and are the safest, highest-impact picks. In terms of popularity, Beating Remnant is the crowd favourite here at a 1.8% pick rate, while Fiddle is slept on at just 0.6% — a strong S-tier pick flying under the radar.

B-tier is led by Ghost Seed, which dominates the meta with a 66.7% win rate on a 0.8% pick rate. They are followed by Sea Glass (66.7%), Lee's Waffle??? (66.7%), Biiig Hug (66.7%), Venerable Tea Set??? (66.7%), Forgotten Soul (60.0%), Storybook (60.0%), and Happy Flower??? (60.0%). The remaining 24 relics in this tier average a 53.7% win rate. These relics are balanced and fully viable with solid execution. In terms of popularity, Venerable Tea Set is the crowd favourite here at a 8.6% pick rate, while Sea Glass is slept on at just 0.6% — a strong B-tier pick flying under the radar.

C-tier is led by Rainbow Ring, which holds steady with a 50.0% win rate on a 2.4% pick rate. They are followed by The Courier (50.0%), Seal of Gold (50.0%), Brilliant Scarf (50.0%), Blood Vial??? (50.0%), Pael's Blood (50.0%), Alchemical Coffer (50.0%), and Regal Pillow (47.1%). The remaining 35 relics in this tier average a 41.9% win rate. These relics are situational and need favourable matchups or team comps to shine. Despite the low ranking, Happy Flower stays popular at a 10.0% pick rate, meaning players overvalue it relative to its C-tier results, while Brilliant Scarf (0.6%) is more rightly avoided.

D-tier is led by Meat on the Bone, which struggles with a 37.5% win rate on a 1.8% pick rate. They are followed by Gremlin Horn (37.5%), Lizard Tail (37.5%), Miniature Tent (36.4%), Sturdy Clamp (36.4%), Razor Tooth (36.4%), War Paint (35.5%), and Potion Belt (35.5%). The remaining 45 relics in this tier average a 31.7% win rate. These relics underperform against the current meta and take extra effort to win with. Despite the low ranking, Meal Ticket stays popular at a 7.7% pick rate, meaning players overvalue it relative to its D-tier results, while Runic Pyramid (0.6%) is more rightly avoided.

F-tier is led by Neow's Bones, which struggles with a 26.9% win rate on a 7.1% pick rate. They are followed by Archaic Tooth (26.7%), Book of Five Rings (25.8%), Kunai (25.0%), Pael's Tears (25.0%), Toolbox (25.0%), Game Piece (25.0%), and Glass Eye (25.0%). The remaining 45 relics in this tier average a 10.8% win rate. These relics are the weakest options this patch and are best avoided in ranked. Despite the low ranking, Divine Right stays popular at a 96.7% pick rate, meaning players overvalue it relative to its F-tier results, while Stone Humidifier (0.6%) is more rightly avoided.