Slay the Spire 2 Defect Relic Tier List
This Slay the Spire 2 relics tier list places 246 relics for October 2026, from S-tier down to F-tier. Placement combines win rate, pick rate and how much match data sits behind each result, so it is not a straight win-rate sort — an entry with a high win rate over few games ranks below a steadier one. The S-tier — the 36 strongest relics right now — features History Course (86.4%), Iron Club (71.4%), Delicate Frond (64.3%), Signet Ring (63.6%), and Jewelry Box (62.5%). History Course posts the single highest win rate at 86.4%. For players hunting an edge, Delicate Frond is the most underrated pick this patch — S-tier results at only a 0.3% pick rate — while Cracked Core looks overrated, popular at 96.3% but landing in F-tier. Rankings update daily from real ranked matches, so every placement reflects current performance rather than a one-off result. Use the tiers below to pick the best relics for your games.
S Tier - Meta Defining
(36)S-tier is led by History Course, which dominates the current data with a 86.4% win rate on a 0.5% pick rate. They are followed by Iron Club (71.4%), Delicate Frond (64.3%), Signet Ring (63.6%), Jewelry Box (62.5%), Distinguished Cape (60.0%), Burning Sticks (56.5%), and Sword of Jade (56.3%). The remaining 28 relics in this tier average a 46.5% win rate. These relics define the current meta and are the safest, highest-impact picks. Popularity within S-tier is uneven: Cloak Clasp is picked in 2.0% of games against 0.3% for Delicate Frond, despite both landing in the same tier.
B Tier - Viable
(37)B-tier is led by Sere Talon, which posts competitive results with a 40.0% win rate on a 0.2% pick rate. They are followed by Fragrant Mushroom (39.8%), Data Disk (39.2%), Sea Glass (39.1%), Choices Paradox (38.9%), Happy Flower??? (38.5%), Anchor??? (37.5%), and Ghost Seed (37.0%). The remaining 29 relics in this tier average a 34.0% win rate. These relics are balanced and fully viable with solid execution. Popularity within B-tier is uneven: Data Disk is picked in 6.2% of games against 0.2% for Sere Talon, despite both landing in the same tier.
C Tier - Situational
(50)C-tier is led by Red Mask, which shows mixed results with a 31.5% win rate on a 8.0% pick rate. They are followed by Toxic Egg (31.5%), Unceasing Top (31.5%), Runic Capacitor (31.4%), Razor Tooth (31.3%), Meat on the Bone (31.1%), Candelabra (31.0%), and Gnarled Hammer (30.6%). The remaining 42 relics in this tier average a 28.0% win rate. These relics are situational and need favourable matchups or team comps to shine. Bag of Preparation stays widely picked at 9.4% despite its C-tier results, while Blood-Soaked Rose sees 0.4%.
D Tier - Below Average
(61)D-tier is led by Strawberry, which trails stronger options with a 26.0% win rate on a 9.0% pick rate. They are followed by Mr. Struggles (26.0%), Gorget (25.9%), Runic Pyramid (25.9%), Gambling Chip (25.9%), Venerable Tea Set (25.7%), Biiig Hug (25.6%), and Vambrace (25.6%). The remaining 53 relics in this tier average a 23.2% win rate. These relics underperform against the current meta and take extra effort to win with. Lantern stays widely picked at 9.2% despite its D-tier results, while Screaming Flagon sees 0.3%.
F Tier - Weak
(62)F-tier is led by Amethyst Aubergine, which currently underperforms with a 19.3% win rate on a 6.3% pick rate. They are followed by Wongo's Mystery Ticket (19.2%), Dingy Rug (19.1%), Massive Scroll (18.9%), Mango??? (18.9%), Bowler Hat (18.8%), Byrdpip (18.6%), and Bone Tea (18.6%). The remaining 54 relics in this tier average a 12.0% win rate. These relics are the weakest options this patch and are best avoided in ranked. Cracked Core stays widely picked at 96.3% despite its F-tier results, while Diamond Diadem sees 0.3%.
