Seraphine - League of Legends Champion
Win Rate
52.1%
Pick Rate
7.6%

Seraphinevs Dr. Mundo

SSupportMage
Patch26.10
Matches3,013,751
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 27, 2026
MethodologyData Methodology

Seraphine vs Dr. Mundo is a decisive matchup in LoL patch 26.10. Seraphine wins with a 60.0% win rate (+20.0%) over Dr. Mundo based on 5 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Dr. Mundo matchup.

Seraphine Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 60.0% win rate in this matchup
Seraphine
60.0% WR
VS
Dr. Mundo vs Seraphine matchup - 40.0% win rate
Dr. Mundo
40.0% WR

Who Wins the Seraphine vs Dr. Mundo Matchup?

Seraphine wins the Seraphine vs Dr. Mundo matchup
Winner
Seraphine
Matches: 5
60.0%
Win Rate
40.0%
3.7
CS / min
3.6
1,060
DMG / min
551
10,091
Gold / game
9,291
332
Heal / min
366
454
DMG Mitigated / min
1,334
0.8
CC / min
0.5
50.0%
Early Game WR
50.0%
66.7%
Late Game WR
33.3%

Seraphine vs Dr. Mundo Matchup Summary

The Seraphine vs Dr. Mundo matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Seraphine wins with a 60.0% win rate compared to Dr. Mundo's 40.0%, giving Seraphine a 20.0 percentage point advantage. Seraphine dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Dr. Mundo players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Dr. Mundo leads by 915 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine players can confidently pick into Dr. Mundo and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Dr. Mundo away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Seraphine vs Dr. Mundo Laning Phase Breakdown

Seraphine wins the laning phase against Dr. Mundo in League of Legends

Seraphine is favored during the laning phase against Dr. Mundo, winning 4 out of 5 key stat categories. Seraphine holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
3.7Seraphine
3.6Dr. Mundo
Seraphine and Dr. Mundo farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
1,060Seraphine
551Dr. Mundo
Seraphine heavily out-damages Dr. Mundo by 508 DMG/min, dominating both short trades and all-in fights. Dr. Mundo should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Seraphine's sustained damage advantage take over.
Economy
10,091Seraphine
9,291Dr. Mundo
Seraphine generates a commanding 800 more gold per game than Dr. Mundo. This substantial economic advantage means Seraphine consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Dr. Mundo should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.8Seraphine
0.5Dr. Mundo
Seraphine provides 0.4 seconds more crowd control per minute than Dr. Mundo, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Seraphine coordinate with their jungler and control the pace of skirmishes.
Sustain
786Seraphine
1,701Dr. Mundo
Dr. Mundo vastly out-sustains Seraphine, healing and mitigating 915 more damage per minute. This massive durability gap means Dr. Mundo can absorb significant punishment and remain in lane while Seraphine is forced to recall. Building grievous wounds early is essential for Seraphine, and focusing on burst trade patterns rather than sustained fights is critical.

Best Seraphine Build Against Dr. Mundo

Ionian Boots of Lucidity is the optimal boots choice against Dr. Mundo, providing the mobility and stats Seraphine needs most in this matchup. The top-performing core items for Seraphine against Dr. Mundo are Echoes of Helia, Moonstone Renewer and Diadem of Songs. This combination gives Seraphine an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Dr. Mundo. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Seraphine vs Dr. Mundo matchup.

Early Game vs Late Game

Early Game
Seraphine
50.0%
+0.0% advantage
Seraphine early game win rateSeraphine50.0%
Dr. Mundo early game win rateDr. Mundo50.0%
Late Game
Seraphine
66.7%
+33.3% advantage
Seraphine late game win rateSeraphine66.7%
Dr. Mundo late game win rateDr. Mundo33.3%

The early game (first 15 minutes) is a toss-up between Seraphine and Dr. Mundo, with Seraphine holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Seraphine is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Dr. Mundo. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

Seraphine holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Dr. Mundo players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Seraphine Runes Against Dr. Mundo

Sorcery rune tree - Seraphine primary runes vs Dr. MundoSorcery
Arcane Comet - best Seraphine rune vs Dr. MundoManaflow Band - best Seraphine rune vs Dr. MundoTranscendence - best Seraphine rune vs Dr. MundoScorch - best Seraphine rune vs Dr. Mundo
Inspiration rune tree - Seraphine secondary runes vs Dr. MundoInspiration
Biscuit Delivery - best Seraphine rune vs Dr. MundoCosmic Insight - best Seraphine rune vs Dr. Mundo
100.0% WR

Running Sorcery primary with Inspiration secondary allows Seraphine to press their advantage against Dr. Mundo, amplifying the strengths that make this a favorable matchup.


Seraphine matchup data for League of Legends patch 26.10. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.

Seraphine matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
50.15%1,0191.64569,36045.9%53.1%
48.30%8821.44648,84447.8%48.7%
49.42%6841.55069,34848.7%50.0%
53.81%6301.44869,17654.6%53.2%
54.65%6241.44999,18359.5%50.3%
50.45%5531.54679,18148.7%51.7%
52.10%4991.44989,21354.3%50.4%
50.43%4661.44328,72855.4%46.6%
50.98%4621.85139,61144.6%55.6%
49.00%4491.54709,25044.6%53.0%
51.47%4431.44728,54453.7%49.1%
55.89%4331.44969,09257.1%54.9%
45.75%4001.55039,07647.7%44.3%
52.13%3281.54679,24147.6%54.9%
53.87%3231.33748,65960.3%48.6%
54.66%3221.34308,98558.8%51.6%
43.95%3141.44558,72142.6%45.3%
54.02%3111.44639,03454.0%54.1%
50.51%2931.75609,32350.0%50.9%
57.88%2921.45059,74063.3%54.6%
52.75%2731.45138,96755.3%50.4%
60.00%2701.84929,46858.0%61.6%
50.19%2591.55909,05450.5%50.0%
50.39%2561.64789,59351.0%50.0%
56.39%2271.54999,34957.6%55.5%
60.64%1884.262310,99759.8%61.3%
52.97%1851.44709,05759.7%48.1%
55.62%1781.45008,84957.6%53.8%
59.26%1621.44859,38267.6%52.3%
51.32%1521.45039,12656.1%47.7%
50.36%1391.44489,08158.7%43.4%
54.26%1291.44929,17642.6%62.7%
51.97%1271.35259,18854.5%50.0%
47.11%1211.54819,72350.0%45.1%
51.33%1136.585111,80850.0%52.3%
42.86%1121.44738,76840.7%44.8%
42.57%1011.84749,52250.0%37.7%
49.48%976.380112,07247.9%51.0%
55.91%934.068910,92467.6%48.2%
55.56%905.272211,63051.4%58.2%
48.78%821.35028,68950.0%47.7%
48.78%821.44649,09250.0%47.9%
57.69%785.676012,32144.8%65.3%
49.33%753.160510,49354.5%45.2%
52.70%742.05849,14455.6%50.0%
52.78%721.75349,69040.0%61.9%
50.75%671.55469,09737.5%58.1%
56.06%661.94759,67959.3%53.9%
55.74%616.579411,80361.3%50.0%
44.44%544.470912,47940.9%46.9%
55.77%522.55049,71055.0%56.3%
58.33%482.04679,67055.6%60.0%
62.50%482.64709,36760.9%64.0%
46.51%434.975211,36935.7%51.7%
65.00%404.261210,37650.0%73.1%
47.37%382.36969,43647.1%47.6%
52.78%366.581612,37750.0%54.5%
36.11%361.54559,16635.3%36.8%
51.43%354.760310,30147.1%55.6%
37.14%352.451110,05933.3%40.0%
42.86%351.752910,53150.0%40.7%
69.70%331.442310,85370.0%69.6%
53.13%322.75309,60446.7%58.8%
56.25%321.86329,91457.1%55.6%
64.52%316.587813,13660.0%66.7%
54.84%311.348010,10845.5%60.0%
63.33%306.283412,93370.0%60.0%
56.67%306.179412,09656.3%57.1%
55.17%296.381012,47650.0%61.5%
48.15%271.753810,04645.5%50.0%
53.85%265.573310,73950.0%58.3%
44.00%255.575511,99550.0%41.2%
60.87%235.067311,41250.0%64.7%
45.45%222.26579,31345.5%45.5%
54.55%225.665110,76464.3%37.5%
50.00%224.375110,63242.9%53.3%
57.14%216.686912,17566.7%44.4%
47.62%211.64358,83136.4%60.0%
47.37%194.86229,45737.5%54.5%
63.16%193.66639,04054.5%75.0%
47.37%192.147810,52750.0%46.7%
63.16%191.453010,08442.9%75.0%
55.56%186.675612,70075.0%40.0%
66.67%183.04999,45680.0%50.0%
61.11%183.45219,17050.0%70.0%
70.59%176.076112,36171.4%70.0%
56.25%167.176510,73975.0%50.0%
43.75%161.45609,71816.7%60.0%
43.75%164.04259,55555.6%28.6%
68.75%165.372911,05242.9%88.9%
56.25%161.24858,45562.5%50.0%
40.00%152.25189,43542.9%37.5%
40.00%153.361010,75057.1%25.0%
50.00%145.993012,77571.4%28.6%
46.15%131.252210,10133.3%50.0%
69.23%132.948710,12077.8%50.0%
76.92%134.378311,970100.0%66.7%
69.23%135.875710,75650.0%85.7%
38.46%134.861911,4660.0%45.5%
50.00%126.283111,35466.7%33.3%
54.55%114.773511,15850.0%60.0%
72.73%116.478814,37060.0%83.3%
72.73%114.462811,66366.7%75.0%
72.73%115.565210,752100.0%57.1%
36.36%116.488012,09660.0%16.7%
72.73%111.466411,29066.7%80.0%
36.36%112.468310,6300.0%44.4%
50.00%102.468410,62333.3%57.1%
30.00%101.54218,79350.0%16.7%
50.00%105.671711,35950.0%50.0%
60.00%103.266711,06833.3%71.4%
50.00%103.468210,8490.0%71.4%
66.67%91.95029,24080.0%50.0%
55.56%92.561310,07175.0%40.0%
62.50%82.667410,785100.0%40.0%
50.00%82.94978,86150.0%50.0%
75.00%81.443310,34950.0%83.3%
37.50%84.552510,981100.0%16.7%
25.00%81.33868,29350.0%0.0%
71.43%71.759111,8080.0%71.4%
28.57%71.65009,1090.0%40.0%
85.71%72.659311,287100.0%80.0%
42.86%73.262610,25850.0%33.3%
42.86%73.47778,18060.0%0.0%
57.14%72.055711,29775.0%33.3%
71.43%75.668510,817100.0%33.3%
66.67%62.25088,36275.0%50.0%
33.33%61.33968,7540.0%40.0%
50.00%63.86668,06640.0%100.0%
50.00%66.282811,70433.3%66.7%
33.33%61.75579,0110.0%66.7%
60.00%53.71,06010,09150.0%66.7%
80.00%51.95429,88950.0%100.0%
40.00%51.354910,03150.0%33.3%

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Seraphine vs Dr. Mundo - Frequently Asked Questions

How does Seraphine do against Dr. Mundo in League of Legends?

Seraphine wins the Seraphine vs Dr. Mundo matchup with a 60.0% win rate compared to Dr. Mundo's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Seraphine do against Dr. Mundo in the early game?

In the early game, Seraphine has the advantage against Dr. Mundo with a 50.0% win rate versus 50.0%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Seraphine do against Dr. Mundo in the late game?

In the late game, Seraphine takes over the Seraphine vs Dr. Mundo matchup with a 66.7% win rate compared to 33.3%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Seraphine vs Dr. Mundo matchup?

Seraphine wins the matchup against Dr. Mundo with a 60.0% win rate in League of Legends patch 26.10. The 20.0 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Seraphine build against Dr. Mundo?

The best Seraphine build against Dr. Mundo includes Echoes of Helia, Moonstone Renewer, Diadem of Songs with Ionian Boots of Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Seraphine runes against Dr. Mundo?

The best Seraphine runes against Dr. Mundo use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Seraphine vs Dr. Mundo matchup. See the full rune breakdown in the matchup comparison above.

Does Seraphine counter Dr. Mundo?

Yes, Seraphine has a favorable matchup against Dr. Mundo with a 60.0% win rate. Seraphine strongly counters Dr. Mundo in lane based on current patch 26.10 data.

How do I play Seraphine against Dr. Mundo?

When playing Seraphine against Dr. Mundo, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.